{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:27:12Z","timestamp":1780964832208,"version":"3.54.1"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,11,6]],"date-time":"2006-11-06T00:00:00Z","timestamp":1162771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report on 2 essential tremor patients who experienced marked improvement in upper extremity tremor with the use of pregabalin (Lyrica, PGB). On PGB 200 mg\/day, tremor amplitude was reduced by at least 40% in the worst affected hand in both patients as measured by accelerometry. Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn\u2013Tolosa\u2013Marin Part I scores were markedly improved. \u00a9 2006 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21211","type":"journal-article","created":{"date-parts":[[2006,11,6]],"date-time":"2006-11-06T13:19:36Z","timestamp":1162819176000},"page":"139-141","source":"Crossref","is-referenced-by-count":17,"title":["Pregabalin (Lyrica) in the treatment of essential tremor"],"prefix":"10.1002","volume":"22","author":[{"given":"Theresa A.","family":"Zesiewicz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L.","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Hauser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica A.","family":"Pease Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly L.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,22]]},"reference":[{"issue":"3","key":"e_1_2_6_2_2","first-page":"2","article-title":"Consensus statement of the Movement Disorder Society on tremor. Ad Hoc Scientific Committee","volume":"13","author":"Deuschl G","year":"1998","journal-title":"Mov Disord"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000163769.28552.CD"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200523625"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01273153"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199908)46:2<249::AID-ANA15>3.0.CO;2-C"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.56.4.475"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8257(200007)15:4<678::AID-MDS1012>3.0.CO;2-0"},{"key":"e_1_2_6_9_2","volume-title":"Physicians' Desk Reference","year":"2005"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjopharm.2005.12.008"},{"key":"e_1_2_6_11_2","first-page":"218","volume-title":"ECDEU Assessment Manual for Psychopharmacology","author":"Guy W","year":"1976"},{"key":"e_1_2_6_12_2","first-page":"725","article-title":"Standardization of a neuromotor test battery: the CATSYS system","volume":"21","author":"Despres C","year":"2000","journal-title":"Neurotoxicology"},{"key":"e_1_2_6_13_2","first-page":"43633","article-title":"Schedules of controlled substances: placement of pregabalin into schedule V. Final rule","volume":"70","author":"Drug Enforcement Administration, Department of Justice","year":"2005","journal-title":"Fed Regist"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21211","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:58:26Z","timestamp":1760968706000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["10.1002\/mds.21211"],"URL":"https:\/\/doi.org\/10.1002\/mds.21211","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}