{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:35:47Z","timestamp":1790667347297,"version":"4.1.0"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,1,30]],"date-time":"2007-01-30T00:00:00Z","timestamp":1170115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2007,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This is a single case report of a patient with spinocerebellar ataxia type 2 (SCA2) and severe tremor. Whereas disease progression with prevailing ataxia and dysmetria was slow over the first symptomatic 6 years, 6 months prior to operation were characterized by the development of a severe, debilitating postural tremor rendering the patient unable to independently sit, stand, speak, or swallow. Deep brain stimulation (DBS) at a subthalamic\u2013thalamic electrode position almost completely arrested her tremor. The patient regained the functional state prior to her rapid disease progression allowing a restricted range of daily activities. Her condition has remained approximately stable over the two postoperative years to date. In addition to the efficacy of DBS on cerebellar tremor, the results illustrate a remarkable improvement of the patient's general condition and independence.<\/jats:p>","DOI":"10.1002\/mds.21338","type":"journal-article","created":{"date-parts":[[2007,2,2]],"date-time":"2007-02-02T17:48:00Z","timestamp":1170438480000},"page":"732-735","source":"Crossref","is-referenced-by-count":62,"title":["Subthalamic\u2010thalamic DBS in a case with spinocerebellar ataxia type 2 and severe tremor\u2014A unusual clinical benefit"],"prefix":"10.1002","volume":"22","author":[{"given":"Hans\u2010Joachim","family":"Freund","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utako B.","family":"Barnikol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Nolte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Treuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Auburger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Tass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madjid","family":"Samii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Sturm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,25]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.9.1369"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10192"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2003.99.3.0566"},{"issue":"2","key":"e_1_2_8_5_2","first-page":"ONS\u2010280","article-title":"Dual electrode thalamic deep brain stimulation for the treatment of posttraumatic and multiple sclerosis tremor","volume":"58","author":"Foote KD","year":"2006","journal-title":"Neurosurgery"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2003.99.4.0708"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2005.08.006"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2002.96.2.0269"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1196-285"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2978-04.2004"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21338","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21338","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:06:44Z","timestamp":1760958404000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4,15]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,4,15]]}},"alternative-id":["10.1002\/mds.21338"],"URL":"https:\/\/doi.org\/10.1002\/mds.21338","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4,15]]}}}