{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:45:23Z","timestamp":1761007523202,"version":"build-2065373602"},"reference-count":63,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,2,8]],"date-time":"2007-02-08T00:00:00Z","timestamp":1170892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2007,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Constantin von Economo's (CvE) main scientific achievements were his studies on the cytoarchitectonics of the cerebral cortex, sleep, and encephalitis lethargica (EL). He found a close relationship between motor symptoms and psychiatric and behavioral disorders in EL and postencephalitic Parkinsonism and identified the underlying neuropathology in the diencephalon and the brainstem. In agreement with Tretiakoff's findings in Parkinson's disease, CvE related postencephalitic Parkinsonism to neuronal loss in the substantia nigra. Several of CvE's early, less well\u2010known publications also deal with the basal ganglia and movement disorders. He demonstrated in rabbits that the substantia nigra modulates automatization, coordination, and succession of masticatory movements and swallowing. In a study on the effects of experimental lesions of the cerebral peduncle in cats and monkeys, CvE hypothesized a corticotegmental pathway that maintains motor functions after pyramidal tract lesions. Recent studies have identified this pathway, which ends in the pedunculopontine nucleus. In a study on posthemiplegic chorea, CvE discussed various pathophysiological hypotheses that partly resemble modern concepts of chorea. In a clinicopathological study on Wilson's disease, CvE traced the striofugal fibers and visualized the basal ganglia outflow pathways. CvE was an outstanding multidisciplinary movement disorder specialist who contributed substantially to modern basal ganglia research. \u00a9 2007 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21352","type":"journal-article","created":{"date-parts":[[2007,2,9]],"date-time":"2007-02-09T02:30:44Z","timestamp":1170988244000},"page":"469-475","source":"Crossref","is-referenced-by-count":9,"title":["Constantin von Economo's contribution to the understanding of movement disorders"],"prefix":"10.1002","volume":"22","author":[{"given":"Gerhard","family":"Ransmayr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,3,27]]},"reference":[{"key":"e_1_2_11_2_2","first-page":"614","article-title":"Quarante cas d'enc\u00e9phalo\u2010my\u00e9lite subaigue","volume":"41","author":"Cruchet R","year":"1917","journal-title":"Bull Mem Soc Med Hop Paris"},{"key":"e_1_2_11_3_2","first-page":"65","article-title":"Dix cas d' encephalite epidemique avec autopsie","volume":"2","author":"Urechia CL","year":"1921","journal-title":"Arch Inter Neurol"},{"volume-title":"Th\u00e9odorid\u00e8s J. Constantin von Economo. The man and the scientist","year":"1979","author":"van Bogaert L","key":"e_1_2_11_4_2"},{"key":"e_1_2_11_5_2","first-page":"1885","article-title":"Nachbehandlung der Kopfverwundeten","volume":"69","author":"von Economo C","year":"1919","journal-title":"Wien Med Wochenschr"},{"key":"e_1_2_11_6_2","first-page":"581","article-title":"Die Encephalitis lethargica","volume":"30","author":"von Economo C","year":"1917","journal-title":"Wien Klin Wochenschr"},{"volume-title":"Die Cytoarchitektonik der Hirnrinde des erwachsenen Menschen","year":"1927","author":"von Economo C","key":"e_1_2_11_7_2"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02322305"},{"key":"e_1_2_11_9_2","first-page":"778","article-title":"Encephalitis lethargica","volume":"17","author":"von Economo C","year":"1923","journal-title":"Wien Med Wochenschr"},{"key":"e_1_2_11_10_2","first-page":"253","article-title":"Die Encephalitis lethargica (Festschrift Obersteiner, Part I)","volume":"38","author":"von Economo C","year":"1917","journal-title":"Jahrb Psych Nervenkr"},{"key":"e_1_2_11_11_2","first-page":"281","article-title":"Zur Entwicklung der Vogelhypophyse","volume":"108","author":"von Economo C","year":"1899","journal-title":"Sitzungsbericht Kaiserl Akad Wiss Wien, Math\u2010Naturwiss"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01659665"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-002-0088-x"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2003.08.058"},{"volume-title":"Contribution \u00e1 l'\u00e9tude de l'anatomie pathologique du locus niger Soemmering avec quelques relatives \u00e0 la pathologie des troubles musculaires et de la maladie de Parkinson","year":"1919","author":"Tretiakoff C","key":"e_1_2_11_15_2"},{"key":"e_1_2_11_16_2","first-page":"274","article-title":"Zur Physiologie und Anatomie des Mittelhirns. Pesdurchtrennung mit Rindenreizungen, experimentelle Chorea, Beitr\u00e4ge zur Faseranatomie des Hirnstammes","volume":"46","author":"von Economo C","year":"1910","journal-title":"Arch f Psychiat Nervenkr"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01679934"},{"key":"e_1_2_11_18_2","first-page":"181","article-title":"\u00dcber den Hirnmechanismus der Mobilit\u00e4t","volume":"20","author":"Probst M","year":"1901","journal-title":"Jahrb Psych Neurol"},{"volume-title":"Untersuchungen \u00fcber die Leitungsbahn des Truncus cerebri und ihren Zusammenhang mit denen der Medulla spinalis und des Cortex cerebri","year":"1904","author":"Lewandowsky MH","key":"e_1_2_11_19_2"},{"volume-title":"Die Funktion des zentralen Nervensystems","year":"1907","author":"Lewandowsky MH","key":"e_1_2_11_20_2"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(00)00099-3"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.9.1767"},{"key":"e_1_2_11_23_2","first-page":"141","article-title":"\u00dcber die Beteiligung der gro\u03b2en basalen Gehirnganglien bei Bewegungsst\u00f6rungen\u2010insbesondere bei Chorea","volume":"14","author":"Anton G","year":"1896","journal-title":"Jahrb Psych Neurol"},{"key":"e_1_2_11_24_2","first-page":"329","article-title":"Zur Pathologie der Hirnschenkelhaube","volume":"9","author":"Halban H","year":"1902","journal-title":"Arbeiten aus dem Neurologischen Institute der Wiener Universit\u00e4t"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.1159\/000228978"},{"volume-title":"Anatomie des centres nerveux","year":"1901","author":"D\u00e9j\u00e9rine J","key":"e_1_2_11_26_2"},{"key":"e_1_2_11_27_2","first-page":"103","article-title":"\u00dcber die zentralen Sinnesbahnen und Sinneszentren des menschlichen Gehirnes","volume":"115","author":"Probst M","year":"1906","journal-title":"Sitzungsbericht der Wiener Akademie der Wissenschaften"},{"volume-title":"Anleitung beim Studium des Baus der nerv\u00f6sen Centralorgane im gesunden und kranken Zustande. 4. Auflage","year":"1901","author":"Obersteiner H","key":"e_1_2_11_28_2"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.1159\/000228601"},{"key":"e_1_2_11_30_2","first-page":"429","article-title":"Beitrag zur Kasuistik und zur Erkl\u00e4rung der posthemiplegischen Chorea","volume":"12","author":"von Economo K","year":"1910","journal-title":"Wien Klin Wochenschr"},{"volume-title":"Topographische Diagnostik der Hirnkrankheiten. Eine klinische Studie","year":"1879","author":"Nothnagel H","key":"e_1_2_11_31_2"},{"key":"e_1_2_11_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01668794"},{"volume-title":"A treatise on diseases of the nervous system","year":"1874","author":"Hammond WA","key":"e_1_2_11_33_2"},{"volume-title":"Handbuch der Nervenkrankheiten. Band 2","year":"1892","author":"Gowers WR","key":"e_1_2_11_34_2"},{"volume-title":"Gehirnpathologie","year":"1905","author":"von Monakow C","key":"e_1_2_11_35_2"},{"key":"e_1_2_11_36_2","doi-asserted-by":"publisher","DOI":"10.1159\/000221055"},{"key":"e_1_2_11_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/117.4.859"},{"key":"e_1_2_11_38_2","first-page":"182","article-title":"Zur Lehre von den Funktionen des Kleinhirns","volume":"18","author":"Pineles F","year":"1899","journal-title":"Jahrb Psych Neurol"},{"key":"e_1_2_11_39_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380203"},{"key":"e_1_2_11_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10327"},{"key":"e_1_2_11_41_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20301"},{"key":"e_1_2_11_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh402"},{"key":"e_1_2_11_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70494-X"},{"key":"e_1_2_11_44_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02869672"},{"key":"e_1_2_11_45_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/34.4.295"},{"key":"e_1_2_11_46_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01926725"},{"volume-title":"Die Funktion der Nervencentra. Band 2","year":"1909","author":"von Bechterew W","key":"e_1_2_11_47_2"},{"volume-title":"Vorlesungen \u00fcber den Bau der nerv\u00f6sen Zentralorgane des Menschen und der Tiere. 7","year":"1911","author":"Edinger L","key":"e_1_2_11_48_2"},{"key":"e_1_2_11_49_2","doi-asserted-by":"crossref","DOI":"10.5962\/bhl.title.48637","volume-title":"Histologie du syst\u00e8me nerveux de l'homme et des vert\u00e9br\u00e9s","author":"Cajal R y","year":"1909"},{"key":"e_1_2_11_50_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/36.3-4.427"},{"key":"e_1_2_11_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(90)90107-L"},{"key":"e_1_2_11_52_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.13-08-03222.1993"},{"key":"e_1_2_11_53_2","first-page":"138","article-title":"\u00dcber die Rinden\u2010Sehh\u00fcgelfasern des Riechfeldes, \u00fcber das Gew\u00f6lbe, die Zwinge, die Randbogenfasern, \u00fcber die Schweifenkernfaserung und \u00fcber die Vertheilung der Pyramidenfasern im Pyramidenareal","author":"Probst M","year":"1903","journal-title":"Arch Anat Physiol, Anatom Abtheilung"},{"key":"e_1_2_11_54_2","first-page":"659","article-title":"Zur Frage von den Leitungsbahnen des Corpus striatum","volume":"30","author":"Gr\u00fcnstein AM","year":"1911","journal-title":"Neurol Centralbl"},{"key":"e_1_2_11_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2005.06.006"},{"key":"e_1_2_11_56_2","article-title":"Quelques consid\u00e9rations g\u00e9n\u00e9rales \u00e0 propos du syndr\u00f4me du corps stri\u00e9","author":"Vogt C","year":"1911","journal-title":"Jahrb Psych Neurol 18, Erg\u00e4nzungsheft, 4"},{"key":"e_1_2_11_57_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02872971"},{"key":"e_1_2_11_58_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02896352"},{"volume-title":"Die Encephalitis lethargica, ihre Nachkrankheiten und ihre Behandlung","year":"1929","author":"von Economo C","key":"e_1_2_11_59_2"},{"key":"e_1_2_11_60_2","first-page":"866","article-title":"Neue Beitr\u00e4ge zur Encephalitis lethargica","volume":"36","author":"von Economo C","year":"1917","journal-title":"Neurol Centralbl"},{"key":"e_1_2_11_61_2","first-page":"1311","article-title":"Ein Fall von chronisch schubweise verlaufender Encephalitis lethargica","volume":"66","author":"von Economo C","year":"1919","journal-title":"M\u00fcnch Med Wochenschr"},{"key":"e_1_2_11_62_2","first-page":"393","article-title":"Grippe\u2010Encephalitis und Encephalitis lethargica","volume":"32","author":"von Economo C","year":"1919","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_11_63_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/60.7.696"},{"key":"e_1_2_11_64_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh008"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21352","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:02:31Z","timestamp":1760968951000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,15]]},"references-count":63,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,3,15]]}},"alternative-id":["10.1002\/mds.21352"],"URL":"https:\/\/doi.org\/10.1002\/mds.21352","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[2007,3,15]]}}}