{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T08:22:26Z","timestamp":1774426946586,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2007,5,21]],"date-time":"2007-05-21T00:00:00Z","timestamp":1179705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2007,7,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Clinical literature suggests an association between essential tremor (ET) and Parkinson's disease (PD), and recent pathological studies describe Lewy bodies in some ET patients. If some ET were an expression of Lewy body disease, one could hypothesize that ET patients who develop parkinsonism would more likely develop PD (a Lewy body disease) than non\u2010Lewy body forms of parkinsonism. The objective was to compare the proportions of patients with PD vs. Parkinson\u2010plus syndromes who had diagnoses of ET. Retrospective chart review at the Neurological Institute (NI) of New York. A larger proportion of the 210 PD than 210 Parkinson\u2010plus syndrome patients had kinetic tremor on examination (119 [56.7%] vs. 70 [33.3%], <jats:italic>P<\/jats:italic> &lt; 0.001). Patients with PD were more likely to have a prior diagnosis of ET than were patients with Parkinson\u2010plus syndromes (7.1% vs. 2.4%, OR 3.16, 95% CI 1.13\u20138.85, <jats:italic>P<\/jats:italic> = 0.02) and more likely to have a diagnosis of ET assigned by an NI neurologist (5.3% vs. 0.0%, OR 12.85, 95% CI 1.66\u201399.8, <jats:italic>P<\/jats:italic> = 0.001). Patients with PD were three to thirteen times more likely to have diagnoses of ET than were patients with Parkinson\u2010plus syndromes. These data further confirm the link between ET and PD, and possibly, between ET and Lewy body disease. \u00a9 2007 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21383","type":"journal-article","created":{"date-parts":[[2007,5,21]],"date-time":"2007-05-21T18:43:09Z","timestamp":1179772989000},"page":"1402-1407","source":"Crossref","is-referenced-by-count":40,"title":["Prevalence of essential tremor in patients with Parkinson's disease vs. Parkinson\u2010plus syndromes"],"prefix":"10.1002","volume":"22","author":[{"given":"Elan D.","family":"Louis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Frucht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,5,21]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1353-8020(02)00057-3"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.61.7.931"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20365"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-199302000-00003"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410170404"},{"key":"e_1_2_6_7_2","article-title":"Exploring the relationship between essential tremor and Parkinson's disease","author":"Shahed J","year":"2006","journal-title":"Parkinsonism Relat Disord"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.046292"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.6.1004"},{"issue":"5","key":"e_1_2_6_10_2","first-page":"A537","article-title":"Pathological investigation of essential tremor","volume":"62","author":"Ross GW","year":"2004","journal-title":"Neurology"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000218162.80315.b9"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440324"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2005.03.013"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.9.1453"},{"key":"e_1_2_6_15_2","first-page":"34","volume-title":"The comprehensive management of Parkinson's disease","author":"Stern MB","year":"1978"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.17.5.427"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150070053"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.8.1237"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000033798.85208.F2"},{"key":"e_1_2_6_20_2","first-page":"84","article-title":"Early cognitive changes and nondementing behavioral abnormalities in Parkinson's disease","volume":"96","author":"Levin BE","year":"2005","journal-title":"Adv Neurol"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000192393.05850.ec"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.3.405"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.63.8.1100"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1995.00540360079019"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21383","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21383","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mds.21383","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21383","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:13:57Z","timestamp":1760951637000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,21]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2007,7,30]]}},"alternative-id":["10.1002\/mds.21383"],"URL":"https:\/\/doi.org\/10.1002\/mds.21383","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,21]]}}}