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The decision to treat was based on his progressive neurological impairment (left sided weakness secondary to spinal cord injury) because of his relentless, violent head jerks. Electrodes were implanted at the level of the medial part of the thalamus (centromedian nucleus, the substantia periventricularis, and the nucleus ventro\u2010oralis internus). DBS resulted in a substantial reduction of tics. These data show that bilateral DBS of the thalamus can have a good effect on severe tics in adult patients suffering from intractable TS. \u00a9 2007 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21398","type":"journal-article","created":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T12:49:00Z","timestamp":1182257340000},"page":"1346-1350","source":"Crossref","is-referenced-by-count":95,"title":["Deep brain stimulation in Tourette's syndrome"],"prefix":"10.1002","volume":"22","author":[{"given":"Rizma Jalees","family":"Bajwa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain J.","family":"de Lotbini\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"King","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahman","family":"Jabbari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Quatrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Kunze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Scahill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Leckman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,6,19]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11526-1"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.160.1.65"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurx.2006.01.009"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.6.1175"},{"key":"e_1_2_7_6_2","first-page":"570","volume-title":"Stereotaxy of the human brain: anatomical, physiological and clinical applications","author":"Hassler R","year":"1982"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2003.99.6.1094"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.043273"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20816"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20551"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000176854.24694.95"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.136.3.317"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91175-T"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000206364.19772.39"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2006.01.001"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2006.01620.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2005.04.006"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0502624102"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1042-3680(02)00116-X"},{"key":"e_1_2_7_20_2","unstructured":"MoranKA LeckmanJF VaccarinoFM WaltonK Llin\u00e1sRR.Neuromagnetic correlates of Gilles de la Tourette syndrome. 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