{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:27:31Z","timestamp":1791491251404,"version":"4.3.4"},"reference-count":32,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2007,8,2]],"date-time":"2007-08-02T00:00:00Z","timestamp":1186012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2007,10,31]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Patients with Parkinson's disease (PD) often complain of unsteadiness. This can occur as the result of various neurological dysfunctions, including changes in postural adjustments, loss of postural reflexes, axial akinesia and rigidity, freezing and\/or postural hypotension. In some cases these symptoms remain unexplained, and rare cases of unsteadiness have been attributed to tremor on standing. To delineate this condition, we investigated 11 consecutive PD patients with unexplained unsteadiness because of tremor on standing, seen in our department over a 6\u2010year period. All the patients had detailed clinical and electrophysiological investigations based on surface polygraphic electromyographic recordings. Four patients had fast orthostatic tremor (13\u201318 Hz), one had intermediate orthostatic tremor (8\u20139 Hz), and three had slow orthostatic tremor (4\u20136 Hz). The remaining 3 patients had orthostatic myoclonus, a condition that has not previously been reported in PD. Patients with fast tremor improved on clonazepam. Patients with slow tremor and myoclonus improved on levodopa and sometimes benefited further when clonazepam was added. These observations show the usefulness of neurophysiological investigations for diagnosing and treating unexplained unsteadiness in Parkinson's disease. \u00a9 2007 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21651","type":"journal-article","created":{"date-parts":[[2007,8,2]],"date-time":"2007-08-02T18:16:25Z","timestamp":1186078585000},"page":"2063-2069","source":"Crossref","is-referenced-by-count":68,"title":["Myoclonus or tremor in orthostatism: An under\u2010recognized cause of unsteadiness in Parkinson's disease"],"prefix":"10.1002","volume":"22","author":[{"given":"Smaranda","family":"Leu\u2010Semenescu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Roze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Vidailhet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9\u2010Pierre","family":"Legrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Marc","family":"Trocello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Cochen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Sangla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Apartis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,8,2]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"233","volume-title":"Movement 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