{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T09:23:10Z","timestamp":1768641790789,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T00:00:00Z","timestamp":1228953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2009,1,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The concept of peripheral myoclonus is not yet fully accepted by the medical community because of the difficulty in establishing a cause\u2010and\u2010effect relationship between trauma and subsequent movement disorders. Here, we report two cases of patients suffering from peripheral myoclonus after nerve injury. The first patient experienced myoclonus of the 4th dorsal interosseous muscle several days after trauma to the elbow. The second patient presented myoclonus of the arm stump (combined with phantom\u2010limb pain) 1 year after amputation. In both cases, central nervous system function (spine and brain imaging, somesthetic evoked potentials, EEG back\u2010averaging) was normal. For the second patient, local infiltration of xylocaine and botulinum toxin into the stump scar rapidly stopped myoclonus and pain. Nerve injury induces ephaptic transmission and ectopic excitation. The physiopathological mechanisms of this type of myoclonus involve a peripheral generator that induces central (spinal) generator activity. \u00a9 2008 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21998","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T17:05:28Z","timestamp":1229015128000},"page":"274-277","source":"Crossref","is-referenced-by-count":39,"title":["Myoclonus of peripheral origin: Two case reports"],"prefix":"10.1002","volume":"24","author":[{"given":"Louise","family":"Tyvaert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Krystkowiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francois","family":"Cassim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elise","family":"Houdayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Kreisler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Dest\u00e9e","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Defebvre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,12,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8257(200101)16:1<7::AID-MDS1005>3.0.CO;2-0"},{"key":"e_1_2_6_3_2","first-page":"191","article-title":"Myoclonies rythm\u00e9es du quadriceps en relation avec un envahissement sarcomateux du nerf crural","volume":"133","author":"Said G","year":"1977","journal-title":"Rev Neurol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.288.6412.173"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.48.6.582"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870110514"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199712)20:12<1602::AID-MUS21>3.0.CO;2-0"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.64.5.673"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.1179"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20647"},{"key":"e_1_2_6_11_2","first-page":"196","volume-title":"Movement disorders","author":"Marsden CD","year":"1982"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20234"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(04)00880-4"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(02)00074-1"},{"key":"e_1_2_6_15_2","first-page":"253","article-title":"Painful jumping amputation stumps: pathophysiology of a \u201csore circuit\u201d","volume":"99","author":"Steiner JC","year":"1974","journal-title":"Trans Am Neurol Assoc"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(76)90965-3"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02334403"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1991.00530240051018"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20011"},{"key":"e_1_2_6_20_2","doi-asserted-by":"crossref","unstructured":"TrompettoC Curr\u00e0A BuccolieriA SuppaA AbbruzzeseG BerardelliA.Botulinum toxin changes intrafusal feedback in dystonia: a study with the tonic vibration reflex.2006;21:777\u2013782.","DOI":"10.1002\/mds.20801"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2003.10.008"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21998","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21998","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:59:30Z","timestamp":1760957970000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21998"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,11]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,1,30]]}},"alternative-id":["10.1002\/mds.21998"],"URL":"https:\/\/doi.org\/10.1002\/mds.21998","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,11]]}}}