{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:30:56Z","timestamp":1787725856971,"version":"build-2784847793"},"reference-count":50,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T00:00:00Z","timestamp":1257292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2009,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Morphometric findings in Tourette's syndrome (TS) are still inconsistent probably due to differences in analysis approaches as well as several confounders (coexisting psychiatric conditions, medication status, etc.). Our aim was to identify possible morphometric changes in a well\u2010defined sample of drug\u2010na\u00efve boys with \u201cpure\u201d TS. High\u2010resolution structural magnetic resonance images of 38 boys with TS were compared with those of 38 healthy boys matched for age and IQ using voxel\u2010based morphometry (VBM). Coexisting psychiatric conditions and previous medication were excluded. The inclusion of 10\u2010 to 15\u2010year\u2010old boys minimized the well known compensatory changes due to tic suppression over many years. VBM analyses revealed no differences between the treatment na\u00efve boys with \u201cpure\u201d TS and healthy controls. Brain morphology is not altered in boys with \u201cpure\u201d TS. Further studies should reveal whether previous findings might be ascribed to confounding factors like coexisting psychiatric conditions or long\u2010term compensatory mechanisms due to voluntary tic suppression. \u00a9 2009 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.22847","type":"journal-article","created":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T17:13:33Z","timestamp":1257354813000},"page":"2398-2403","source":"Crossref","is-referenced-by-count":34,"title":["No brain structure abnormalities in boys with Tourette's syndrome: A voxel\u2010based morphometry 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