{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:34:28Z","timestamp":1778618068216,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2009,12,11]],"date-time":"2009-12-11T00:00:00Z","timestamp":1260489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institute of Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2010,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Levodopa\u2010induced dyskinesias (LIDs) are frequent in parkinsonian patients and may result from an aberrant plasticity. Brain\u2010derived neurotrophic factor (BDNF) represents a likely candidate to subserve neuroadaptive processes encountered in LIDs. We compared striatal BDNF levels measured by ELISA in levodopa\u2010treated 1\u2010methyl\u20104\u2010phenyl\u20101,2,3,6\u2010tetrahydropyridine (MPTP) monkeys having developed LIDs compared with animals where LIDs were prevented by the addition of CI\u20101041 (NR1A\/2B NMDA receptor antagonist) or low doses of cabergoline (dopamine D2 receptor agonist). We observed reduced striatal BDNF concentrations in levodopa\u2010treated MPTP monkeys with or without LIDs, suggesting that levodopa treatment is associated with reduced striatal BDNF levels and is independent of dyskinesias. \u00a9 2009 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.22885","type":"journal-article","created":{"date-parts":[[2009,12,11]],"date-time":"2009-12-11T15:42:54Z","timestamp":1260546174000},"page":"116-121","source":"Crossref","is-referenced-by-count":11,"title":["BDNF levels are not related with levodopa\u2010induced dyskinesias in MPTP monkeys"],"prefix":"10.1002","volume":"25","author":[{"given":"Pershia","family":"Samadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Morissette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"L\u00e9vesque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Th\u00e9r\u00e8se","family":"Di Paolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,1,25]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-1931(00)00026-4"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2005.06.003"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1990.tb07423.x"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.6A6952.2006"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/39885"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-07-02295.1997"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10589"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2003.10.007"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.2174\/1381612024607072"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902220208"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20654"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2007.02.005"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2003.07.003"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2004.08.018"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/35075076"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm875"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.1998.00264.x"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2000.740582.x"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2003.01599.x"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1856-06.2006"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.154294"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.22885","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.22885","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.22885","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:36:27Z","timestamp":1760970987000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.22885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,15]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1,15]]}},"alternative-id":["10.1002\/mds.22885"],"URL":"https:\/\/doi.org\/10.1002\/mds.22885","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,15]]}}}