{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:59:36Z","timestamp":1792094376292,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,11,10]],"date-time":"2010-11-10T00:00:00Z","timestamp":1289347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Tourettes Action-United Kingdom and Tourette syndrome Association-USA"},{"name":"Italian version of the Youth Quality of Life Instrument-Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Tourette syndrome (TS) is a neurodevelopmental disorder involving tics, which is frequently accompanied by comorbid obsessive compulsive (OCD) or attention deficit hyperactivity disorder (ADHD). Individuals with TS often report poor quality of life (QoL) in comparison with the general population. This study investigated the clinical correlates of QoL in young people with TS using a self\u2010report multidimensional QoL measure, and a range of clinical scales used to assess tic severity and the symptoms of anxiety, depression, OCD, ADHD and other emotional and behavioral symptoms. Symptoms of depression, OCD, and ADHD appeared to have a widespread negative impact on QoL, but poorer QoL was not associated with increased tic severity. Greater emotional and behavioral difficulties, including symptoms of OCD, were among the best predictors of poor QoL in young people with TS. \u00a9 2010 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.23434","type":"journal-article","created":{"date-parts":[[2010,11,10]],"date-time":"2010-11-10T13:45:19Z","timestamp":1289396719000},"page":"735-738","source":"Crossref","is-referenced-by-count":110,"title":["Clinical correlates of quality of life in Tourette syndrome"],"prefix":"10.1002","volume":"26","author":[{"given":"Clare M.","family":"Eddy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea E.","family":"Cavanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Gulisano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Agodi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Barchitta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Cal\u00ec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary M.","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,11,10]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2001.00147.x"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0145445505279383"},{"key":"e_1_2_7_4_2","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/j.1365-2214.2009.00983.x","article-title":"The quality of life of young people with Tourette syndrome","volume":"35","author":"Cutler D","year":"2009","journal-title":"Child"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22900"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/15374410701279545"},{"issue":"1","key":"e_1_2_7_7_2","first-page":"S231","article-title":"Anxiety and depression in children with Tourette syndrome versus epilepsy\u2014Impact on quality of life, a comparative study","volume":"24","author":"Lavenstein B","year":"2009","journal-title":"Mov Disord"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22487"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1006\/jado.2002.0470"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1006\/jado.2002.0471"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000327890.02893.61"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-198907000-00015"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199704000-00019"},{"key":"e_1_2_7_14_2","volume-title":"Children's Depression Inventory (CDI)","author":"Kovacs M","year":"1992"},{"key":"e_1_2_7_15_2","volume-title":"Rating scales for use in drug studies with children. 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