{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:49:33Z","timestamp":1786978173786,"version":"build-2736575974"},"reference-count":45,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2011,6,28]],"date-time":"2011-06-28T00:00:00Z","timestamp":1309219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2011,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Mutations in the maternally imprinted epsilon\u2010sarcoglycan gene occur in 30%\u201350% of myoclonus\u2010dystonia cases. Psychiatric symptoms, particularly obsessive\u2010compulsive disorder, have been described in some patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We systematically reviewed 22 reports of psychiatric symptoms in myoclonus\u2010dystonia, dividing individuals according to clinical and mutation status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Clinically manifesting mutation carriers demonstrated an excess of psychiatric disorders compared with nonmutation carriers (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001). No differences were seen between non\u2010motor\u2010manifesting carriers and nonmutation carriers with the exception of alcohol excess\/dependence, higher in non\u2010motor\u2010manifesting carriers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The results confirm the association of epsilon\u2010sarcoglycan gene mutations with psychiatric disease and suggest a possible separation of the motor and psychiatric effects. \u00a9 2011 Movement Disorder Society<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.23791","type":"journal-article","created":{"date-parts":[[2011,6,30]],"date-time":"2011-06-30T10:29:28Z","timestamp":1309429768000},"page":"1939-1942","source":"Crossref","is-referenced-by-count":38,"title":["Psychiatric disorders, myoclonus dystonia, and the epsilon\u2010sarcoglycan gene: A systematic review"],"prefix":"10.1002","volume":"26","author":[{"given":"Kathryn J.","family":"Peall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian J.","family":"Waite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek J.","family":"Blake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike J.","family":"Owen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huw 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