{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:15:00Z","timestamp":1761513300179,"version":"build-2065373602"},"reference-count":7,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T00:00:00Z","timestamp":1369785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with anti\u2010N\u2010methyl\u2010D\u2010aspartate\u2010glutamic\u2010receptors (NMDAR) encephalitis often develop complex abnormal movements that may manifest early in the course of illness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods\/Results<\/jats:title><jats:p>A 17\u2010year\u2010old boy developed paroxysmal exercise\u2010induced right foot weakness, without behavioral change. Two weeks later, he had hyperthermia and convulsive status epilepticus. Intravenous valproate resolved the status, but the paroxysmal episodes of right foot weakness persisted. They recurred any time he began running, without any refractory period or other triggering factors. Neurological examination between attacks was normal. Ictal video\u2010polygraphy showed transient loss of lower limb muscle activity without any EEG changes. Results of brain MRI and extensive laboratory tests were normal. NMDAR antibodies were present in liquor and serum. No tumor was found. He was treated with intravenous methylprednisolone plus immunoglobulins with resolution of his symptoms that have not recurred at 8\u2010month follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our case enlarges the spectrum of abnormal movements as presentation of oligosymptomatic anti\u2010NMDAR encephalitis. \u00a9 2013 <jats:italic>Movement<\/jats:italic> Disorder Society<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.25510","type":"journal-article","created":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T15:31:20Z","timestamp":1369841480000},"page":"820-822","source":"Crossref","is-referenced-by-count":11,"title":["Anti\u2013N\u2010methyl\u2010D\u2010aspartate\u2010glutamic\u2010receptor encephalitis presenting as paroxysmal exercise\u2010induced foot weakness"],"prefix":"10.1002","volume":"28","author":[{"given":"Angelo","family":"Labate","sequence":"first","affiliation":[{"name":"Institute of Neurology University Magna Graecia Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"Quattrone","sequence":"additional","affiliation":[{"name":"Institute of Neurology University Magna Graecia Catanzaro Italy"},{"name":"Institute of Neurological Sciences, National Research Council Mangone Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Dalmau","sequence":"additional","affiliation":[{"name":"Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats (ICREA) Universitat de Barcelona and Institut d'Investigaci\u00f3 Biom\u00e8dica August Pi i Sunyer (IDIBAPS) Hospital Clinic University of Barcelona  Spain"},{"name":"Department of Neurology University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Gambardella","sequence":"additional","affiliation":[{"name":"Institute of Neurology University Magna Graecia Catanzaro Italy"},{"name":"Institute of Neurological Sciences, National Research Council Mangone Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70253-2"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23315"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21756"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000147298.05983.50"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22073"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2009.0268"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh639"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.25510","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.25510","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.25510","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:18:07Z","timestamp":1760951887000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.25510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,29]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1002\/mds.25510"],"URL":"https:\/\/doi.org\/10.1002\/mds.25510","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[2013,5,29]]}}}