{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:37:48Z","timestamp":1790181468790,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T00:00:00Z","timestamp":1429142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","award":["(DFG; GA2031\/1-2)"],"award-info":[{"award-number":["(DFG; GA2031\/1-2)"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Movement Disorders society, Actelion,Ipsen, Pharm Allergan and Merz"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A contribution of aberrant interoceptive awareness to the perception of premonitory urges in Gilles de la Tourette syndrome (GTS) has been hypothesized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We assessed interoceptive awareness in 19 adults with GTS and 25 age\u2010matched healthy controls using the heartbeat counting task. We also used multiple regression to explore whether the severity of premonitory urges was predicted by interoceptive awareness or severity of tics and obsessive\u2010compulsive symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We observed lower interoceptive awareness in GTS compared with controls. Interoceptive awareness was the strongest predictor of premonitory urges in GTS, with greater interoceptive awareness being associated with more urges. Greater tic severity was also associated with higher rates of premonitory urges.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The observed relationship between severity of premonitory urges and interoceptive awareness suggests that interoception might be involved in self\u2010reported premonitory urges in GTS. High levels of interoceptive awareness might reflect a self\u2010attentive capacity to perceive urges. \u00a9 2015 International Parkinson and Movement Disorder Society<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.26228","type":"journal-article","created":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T07:53:20Z","timestamp":1429170800000},"page":"1198-1202","source":"Crossref","is-referenced-by-count":123,"title":["Premonitory urge to tic in tourette's is associated with interoceptive awareness"],"prefix":"10.1002","volume":"30","author":[{"given":"Christos","family":"Ganos","sequence":"first","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology University College London London UK"},{"name":"Department of Neurology University Medical Center Hamburg\u2010Eppendorf (UKE) Hamburg 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