{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:43:33Z","timestamp":1790693013245,"version":"4.1.0"},"reference-count":71,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,4,8]],"date-time":"2016-04-08T00:00:00Z","timestamp":1460073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>To review the emerging role of transcranial MR\u2010guided focused ultrasound as a treatment and research modality for functional neurological disorders, we summarize recent clinical and preclinical studies. Clinical trials have investigated the safety and efficacy of thermal lesions created by transcranial, high\u2010intensity focused ultrasound. Preclinical work has additionally investigated the ability to disrupt the blood\u2013brain barrier and to produce reversible neuromodulation with focused ultrasound utilizing lower intensities. We discuss ongoing trials and future avenues of investigation. \u00a9 2016 International Parkinson and Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.26599","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T14:15:25Z","timestamp":1460297725000},"page":"20-27","source":"Crossref","is-referenced-by-count":53,"title":["The emerging role of transcranial magnetic resonance imaging\u2013guided focused ultrasound in functional neurosurgery"],"prefix":"10.1002","volume":"32","author":[{"given":"David","family":"Weintraub","sequence":"first","affiliation":[{"name":"Department of Neurosurgery University of Virginia Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Jeffrey","family":"Elias","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery University of Virginia Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.neu.0000316285.52865.53"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(09)17525-8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3171\/2010.4.FOCUS10106"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.121.3137.217"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196009012630905"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.127.3289.83"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.122.3179.1091"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1954.11.5.0471"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.10.1.61"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1960.17.2.0213"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.10.3.271"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1959.16.1.0032"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3182672ac9"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20118"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/47\/8\/301"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(02)00503-3"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.426863"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910340606"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-307642"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1300962"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70048-6"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/219149"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.8.JNS132603"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2014.154"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.3171\/2011.10.FOCUS11248"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21801"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/2050-5736-1-24"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.3668316"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318236f0fd"},{"key":"e_1_2_11_31_1","first-page":"91","article-title":"Treatment of essential tremor: are there issues we are overlooking?","volume":"2","author":"Louis ED","year":"2011","journal-title":"Front Neurol"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70322-7"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60544-3"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1600159"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3808"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/2050-5736-2-11"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.8.JNS132603"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001826"},{"key":"e_1_2_11_39_1","unstructured":"A feasibility clinical trial of the management of the medically\u2010refractory dyskinesia symptoms of advanced idiopathic Parkinson's disease with unilateral lesioning of the globus pallidum using the ExAblate transcranial system. 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