{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:22:39Z","timestamp":1777656159786,"version":"3.51.4"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,4,19]],"date-time":"2016-04-19T00:00:00Z","timestamp":1461024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"K\u00f6ln Fortune program"},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["Klinische Forschergruppe KFO 219 [Ti 319\/2-1]"],"award-info":[{"award-number":["Klinische Forschergruppe KFO 219 [Ti 319\/2-1]"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although motor symptoms predominate in essential tremor, increasing evidence indicates additional cognitive deficits. According to the pivotal role of cognitive functioning for temporal information processing and acknowledging the relevance of temporal information processing for movement coordination, we investigated whether essential tremor patients exhibit time reproduction deficits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 24 essential tremor patients and 24 healthy controls performed sub\u2010 and suprasecond visual duration reproduction tasks of 500 to 900 milliseconds and 1.6 to 2.4 seconds, respectively. To differentiate deficient time processing from motor or other cognitive dysfunctions, the average temporal reproduction errors were correlated with tremor severity, immediate and delayed word\u2010list recall performance, and verbal fluency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Essential tremor patients significantly underreproduced sub\u2010 and suprasecond time intervals longer than 800 milliseconds. Moreover, time compression correlated significantly with semantic verbal fluency and word\u2010list retrieval performance, but not with tremor severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Data suggest impaired temporal processing in essential tremor, corroborating evidence for specific cognitive deficits. \u00a9 2016 International Parkinson and Movement Disorder Society<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.26630","type":"journal-article","created":{"date-parts":[[2016,4,19]],"date-time":"2016-04-19T03:41:22Z","timestamp":1461037282000},"page":"1234-1240","source":"Crossref","is-referenced-by-count":10,"title":["Time reproduction deficits in essential tremor patients"],"prefix":"10.1002","volume":"31","author":[{"given":"David J.","family":"Pedrosa","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital Cologne Cologne Germany"},{"name":"Nuffield Department of Clinical Neurosciences University of Oxford Oxford 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