{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:29:49Z","timestamp":1788791389751,"version":"build-2803163510"},"reference-count":61,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,24]],"date-time":"2017-01-24T00:00:00Z","timestamp":1485216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Although essential tremor has been considered the most common movement disorder, it has largely remained a diagnosis of exclusion: many tremor and nontremor features must be absent for the clinical diagnosis to stand. The clinical features of \u201cessential tremor\u201d overlap with or may be part of other tremor disorders and, not surprisingly, this prevalent familial disorder has remained without a gene identified, without a consistent natural history, and without an acceptable pathology or pathophysiologic underpinning. The collective evidence suggests that under the rubric of essential tremor there exists multiple unique diseases, some of which represent cerebellar dysfunction, but for which there is no intrinsic \u201cessence\u201d other than a common oscillatory behavior on posture and action. One approach may be to use the term <jats:italic>essential tremor<\/jats:italic> only as a transitional node in the deep phenotyping of tremor disorders based on historical, phenomenological, and neurophysiological features to facilitate its etiologic diagnosis or serve for future gene\u2010 and biomarker\u2010discovery efforts. This approach deemphasizes essential tremor as a diagnostic entity and facilitates the understanding of the underlying disorders to develop biologically tailored diagnostic and therapeutic strategies. \u00a9 2017 International Parkinson and Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.26919","type":"journal-article","created":{"date-parts":[[2017,1,24]],"date-time":"2017-01-24T01:42:50Z","timestamp":1485222170000},"page":"325-331","source":"Crossref","is-referenced-by-count":90,"title":["Essential pitfalls in \u201cessential\u201d tremor"],"prefix":"10.1002","volume":"32","author":[{"given":"Alberto J.","family":"Espay","sequence":"first","affiliation":[{"name":"UC Gardner Neuroscience Institute Department of Neurology, Gardner Center for Parkinson's Disease and Movement Disorders, University of Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony E.","family":"Lang","sequence":"additional","affiliation":[{"name":"Morton and Gloria Shulman Movement Disorders Center, Toronto Western Hospital and The Edmond J. Safra Program in PD, Toronto, Ontario, Canada, University of Toronto Toronto Ontario Canada"},{"name":"Krembil Research Institute Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Erro","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Biomedicine and Movement Science, University of Verona Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aristide","family":"Merola","sequence":"additional","affiliation":[{"name":"UC Gardner Neuroscience Institute Department of Neurology, Gardner Center for Parkinson's Disease and Movement Disorders, University of Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Fasano","sequence":"additional","affiliation":[{"name":"Morton and Gloria Shulman Movement Disorders Center, Toronto Western Hospital and The Edmond J. 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