{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T13:43:49Z","timestamp":1790430229015,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T00:00:00Z","timestamp":1550016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["6\u20102017\u20100068"],"award-info":[{"award-number":["6\u20102017\u20100068"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Following the emergence of magnetic resonance\u2010guided focused ultrasound as a promising tool for movement disorder surgery, thalamotomy for essential tremor using this technique has become a useful tool based on its efficacy and lack of adverse effects. Here, we summarize the 4\u2010year results of previous reports focusing on the durability of effectiveness of magnetic resonance\u2010guided focused ultrasound thalamotomy for essential tremor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From October 2013 to August 2014, 15 patients with intractable essential tremor were enrolled. Twelve of them completed clinical assessment through 4\u2009years of postoperative follow\u2010up. Tremor severity, task performance, and disability were measured using the Clinical Rating Scale of Tremor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age of the 12 patients was 61.7\u2009\u00b1\u20098.1\u2009years. Maximally delivered energy was 15,552.4\u2009\u00b1\u20096574.1 joules. The mean number of sonications was 17.3\u2009\u00b1\u20091.6. The mean postoperative lesion volume was 82.6 \u00b1 29.023\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      and in 1\u2009year was a mean of 9.667\u2009\u00b1\u20098.573\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      . Four years postoperatively, improvement of the hand tremor score was 56%, that of the disability score was 63%, that of the postural score was 70%, and that of the action score was 63% compared with baseline; all improvements were significant and sustained over the 4\u2010year period after thalamotomy. There was no permanent adverse effect throughout the 4\u2010year follow\u2010up period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Magnetic resonance\u2010guided focused ultrasound thalamotomy exhibits sustained clinical efficacy 4\u2009years after the treatment of intractable essential tremor. Adverse events are generally transient. A large cohort of patients who have undergone magnetic resonance\u2010guided focused ultrasound thalamotomy with longer follow\u2010up is needed to confirm our findings. \u00a9 2019 International Parkinson and Movement Disorder Society<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.27637","type":"journal-article","created":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T14:26:29Z","timestamp":1550067989000},"page":"727-734","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":134,"title":["Four\u2010year follow\u2010up results of magnetic resonance\u2010guided focused ultrasound thalamotomy for essential tremor"],"prefix":"10.1002","volume":"34","author":[{"given":"Yong\u2010Sook","family":"Park","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Chung\u2010Ang University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na Young","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Brain Research Institute, Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Cheol","family":"Na","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Catholic Kwandong University College of Medicine, International St. Mary's Hospital  Incheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Woo","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Brain Research Institute, Yonsei University College of Medicine  Seoul 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