{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:07:53Z","timestamp":1791806873539,"version":"4.3.4"},"reference-count":53,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T00:00:00Z","timestamp":1582502400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006937","name":"National Center for Medical Rehabilitation Research","doi-asserted-by":"publisher","award":["P2CHD086851 National Rehabilitation Research Resou"],"award-info":[{"award-number":["P2CHD086851 National Rehabilitation Research Resou"]}],"id":[{"id":"10.13039\/100006937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006937","name":"National Center for Medical Rehabilitation Research","doi-asserted-by":"publisher","award":["T32 HD071866"],"award-info":[{"award-number":["T32 HD071866"]}],"id":[{"id":"10.13039\/100006937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["K23NS080912"],"award-info":[{"award-number":["K23NS080912"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001288","name":"Parkinson's Disease Foundation","doi-asserted-by":"publisher","award":["Translational Research Grant"],"award-info":[{"award-number":["Translational Research Grant"]}],"id":[{"id":"10.13039\/100001288","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sleep dysfunction is common and disabling in persons with Parkinson's Disease (PD). Exercise improves motor symptoms and subjective sleep quality in PD, but there are no published studies evaluating the impact of exercise on objective sleep outcomes. The goal of this study was to to determine if high\u2010intensity exercise rehabilitation combining resistance training and body\u2010weight interval training, compared with a sleep hygiene control improved objective sleep outcomes in PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Persons with PD (Hoehn &amp; Yahr stages 2\u20133; aged \u226545\u2009years, not in a regular exercise program) were randomized to exercise (supervised 3 times a week for 16\u2009weeks; n = 27) or a sleep hygiene, no\u2010exercise control (in\u2010person discussion and monthly phone calls; n = 28). Participants underwent polysomnography at baseline and post\u2010intervention. Change in sleep efficiency was the primary outcome, measured from baseline to post\u2010intervention. Intervention effects were evaluated with general linear models with measurement of group \u00d7 time interaction. As secondary outcomes, we evaluated changes in other aspects of sleep architecture and compared the effects of acute and chronic training on objective sleep outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The exercise group showed significant improvement in sleep efficiency compared with the sleep hygiene group (group \u00d7 time interaction:\n                      <jats:italic>F<\/jats:italic>\n                      = 16.0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic>d<\/jats:italic>\n                      = 1.08). Other parameters of sleep architecture also improved in exercise compared with sleep hygiene, including total sleep time, wake after sleep onset, and slow\u2010wave sleep. Chronic but not acute exercise improved sleep efficiency compared with baseline.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>High\u2010intensity exercise rehabilitation improves objective sleep outcomes in PD. Exercise is an effective nonpharmacological intervention to improve this disabling nonmotor symptom in PD. \u00a9 2020 International Parkinson and Movement Disorder Society<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.28009","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T13:47:48Z","timestamp":1582552068000},"page":"947-958","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":118,"title":["Randomized, Controlled Trial of Exercise on Objective and Subjective Sleep in Parkinson's Disease"],"prefix":"10.1002","volume":"35","author":[{"given":"Amy W.","family":"Amara","sequence":"first","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham  Birmingham Alabama USA"},{"name":"UAB Center for Exercise Medicine. Birmingham  Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly H.","family":"Wood","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham  Birmingham Alabama USA"},{"name":"UAB Center for Exercise Medicine. Birmingham  Alabama USA"},{"name":"Department of Psychology Samford University  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen","family":"Joop","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raima A.","family":"Memon","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham  Birmingham Alabama USA"},{"name":"Department of Pathology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Pilkington","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Craig","family":"Tuggle","sequence":"additional","affiliation":[{"name":"UAB Center for Exercise Medicine. Birmingham  Alabama USA"},{"name":"Department of Cell, Developmental, and Integrative Biology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Reams","sequence":"additional","affiliation":[{"name":"UAB Center for Exercise Medicine. Birmingham  Alabama USA"},{"name":"Department of Cell, Developmental, and Integrative Biology University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Barrett","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Kinesiology University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur L.","family":"Weltman","sequence":"additional","affiliation":[{"name":"Department of Kinesiology University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Hurt","sequence":"additional","affiliation":[{"name":"UAB Center for Exercise Medicine. Birmingham  Alabama USA"},{"name":"Department of Physical Therapy University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Cutter","sequence":"additional","affiliation":[{"name":"UAB Center for Exercise Medicine. Birmingham  Alabama USA"},{"name":"Department of Biostatistics University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcas M.","family":"Bamman","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham  Birmingham Alabama USA"},{"name":"UAB Center for Exercise Medicine. Birmingham  Alabama USA"},{"name":"Department of Pathology University of Alabama at Birmingham  Birmingham Alabama USA"},{"name":"Geriatric Research, Education, and Clinical Center Birmingham VA Medical Center  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22643"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23135"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-198812000-00004"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-198205020-00003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2016.08.001"},{"key":"e_1_2_7_7_1","volume-title":"Movement Disorders","author":"Bliwise DL","year":"2012"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20412"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3148"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2016-315023"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-017-0461-6"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01277.2013"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.3517"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000644"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25380"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.906179"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-015-9617-6"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2012.00048"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-199621040-00004"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12082"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0000000000001685"},{"key":"e_1_2_7_22_1","unstructured":"Organization WH. 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