{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:49:49Z","timestamp":1786632589221,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T00:00:00Z","timestamp":1606694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T00:00:00Z","timestamp":1606694400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Celiac disease is associated with motor cortex hyperexcitability and neurological manifestations including cortical myoclonus. Electroencephalography abnormalities have been described, but no distinct pattern has been reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We describe the neurophysiological characteristics of 3 patients with celiac\u2010associated cortical myoclonus using electroencephalography, magnetoencephalography, and transcranial magnetic stimulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Electroencephalography in all cases demonstrated lateralized low\u2010amplitude, electropositive beta\u2010frequency polyspike activity over the central head region, corresponding to motor cortex contralateral to the myoclonic limb. Jerk\u2010locked back\u2010averaging demonstrated a preceding cortical potential; magnetoencephalography source localization revealed a cortical generator in the posterior wall of the precentral gyrus for the back\u2010averaged potential and oscillatory abnormality. In 1 patient, cerebellar inhibition of the motor cortex was physiologically normal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Central head oscillatory, low\u2010amplitude, electropositive electroencephalography polyspike activity may be a distinct marker of celiac\u2010related cortical myoclonus and is consistent with celiac\u2010related motor cortex hyperexcitability, which may not necessarily result from cerebellar disinhibition. \u00a9 2020 International Parkinson and Movement Disorder Society<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.28407","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T05:02:59Z","timestamp":1606712579000},"page":"999-1005","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A Distinct\n                    <scp>EEG<\/scp>\n                    Marker of Celiac Disease\u2010Related Cortical Myoclonus"],"prefix":"10.1002","volume":"36","author":[{"given":"Emily","family":"Swinkin","sequence":"first","affiliation":[{"name":"Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital and Division of Neurology, UHN, Division of Neurology University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9766-6252","authenticated-orcid":false,"given":"Karlo J.","family":"Liz\u00e1rraga","sequence":"additional","affiliation":[{"name":"Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital and Division of Neurology, UHN, Division of Neurology University of Toronto  Toronto Ontario Canada"},{"name":"Motor Physiology and Neuromodulation Program, Division of Movement Disorders and Center for Health and Technology (CHeT), Department of Neurology University of Rochester  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musleh","family":"Algarni","sequence":"additional","affiliation":[{"name":"Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital and Division of Neurology, UHN, Division of Neurology University of Toronto  Toronto Ontario Canada"},{"name":"Division of Neurology East Jeddah Hospital  Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Garcia Dominguez","sequence":"additional","affiliation":[{"name":"Mitchell Goldhar MEG Unit, Clinical Neurophysiology Laboratory Toronto Western Hospital, University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3043-9113","authenticated-orcid":false,"given":"Julianne K.","family":"Baarb\u00e9","sequence":"additional","affiliation":[{"name":"Krembil Research Institute University Health Network  Toronto Ontario Canada"},{"name":"Institute of Medical Science, School of Graduate Studies University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Saravanamuttu","sequence":"additional","affiliation":[{"name":"Krembil Research Institute University Health Network  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Chen","sequence":"additional","affiliation":[{"name":"Edmond J. 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