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Although severe hypoxia is detrimental for the brain, physiological adaptations to mild hypoxia are neuroprotective. Herein we discuss, how neuroprotective effects can be induced by hypoxia conditioning and how related approaches have the potential to be harnessed as therapeutic strategies in Parkinson's disease. \u00a9 2021 International Parkinson and Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.28544","type":"journal-article","created":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T11:15:21Z","timestamp":1614424521000},"page":"857-861","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Hypoxia Conditioning as a Promising Therapeutic Target in Parkinson's Disease?"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2889-0151","authenticated-orcid":false,"given":"Johannes","family":"Burtscher","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences University of Lausanne  Lausanne Switzerland"},{"name":"Institute of Sport Sciences, University of Lausanne  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed Muazzam Kamil","family":"Syed","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular and Chemical Biology of Neurodegeneration Brain Mind Institute, EPFL  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilal A.","family":"Lashuel","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular and Chemical Biology of Neurodegeneration Brain Mind Institute, EPFL  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8081-4423","authenticated-orcid":false,"given":"Gr\u00e9goire P.","family":"Millet","sequence":"additional","affiliation":[{"name":"Institute of Sport Sciences, University of Lausanne  Lausanne 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