{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:02:06Z","timestamp":1790794926540,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T00:00:00Z","timestamp":1623456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hyposmia and isolated REM sleep behavior disorder are well\u2010established features of prodromal Parkinson's disease (PD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of the present study was to evaluate whether taste loss (reported in PD and possibly suggesting brain stem involvement) is present at the isolated REM sleep behavior disorder stage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We assessed taste function using the Taste Strip Test (evaluating 4 concentrations of bitter, sweet, sour, and salty) in 44 participants with isolated REM sleep behavior disorder, 19 with PD, and 29 controls. All participants underwent video\u2010polysomnography, standardized questionnaires, and clinical examination, including olfactory assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participants with isolated REM sleep behavior disorder and PD had lower taste scores than controls. There was no difference between isolated REM sleep behavior disorder and PD cohorts, nor was there any correlation between taste and olfaction, age, disease duration, cognition, or autonomic function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrates for the first time the presence of taste impairment in isolated REM sleep behavior disorder that is independent of olfactory dysfunction and comparable to participants with PD. \u00a9 2021 International Parkinson and Movement Disorder Society<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.28692","type":"journal-article","created":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T07:19:40Z","timestamp":1623482380000},"page":"2431-2435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Sweet or Bland Dreams? Taste Loss in Isolated <scp>REM<\/scp>\u2010Sleep Behavior Disorder and Parkinson's Disease"],"prefix":"10.1002","volume":"36","author":[{"given":"Milan","family":"Nigam","sequence":"first","affiliation":[{"name":"Sleep Disorders Unit University Hospital Piti\u00e9\u2010Salp\u00eatri\u00e8re, APHP\u2010Sorbonne  Paris France"},{"name":"Centre for Advanced Research in Sleep Medicine Sacr\u00e9\u2010Coeur Hospital  Montreal Quebec Canada"},{"name":"Department of Neurosciences University of Montreal  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Ayadi","sequence":"additional","affiliation":[{"name":"Sleep Disorders Unit University Hospital Piti\u00e9\u2010Salp\u00eatri\u00e8re, APHP\u2010Sorbonne  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Noiray","sequence":"additional","affiliation":[{"name":"Sleep Disorders Unit University Hospital Piti\u00e9\u2010Salp\u00eatri\u00e8re, 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