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In sensitivity analyses, we excluded early outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 198,099 individuals with HZ and 976,660 matched individuals without HZ (median age 67.0\u2009years (interquartile range [IQR 61.4\u201375.7]); 94% male; median follow\u2010up 4.2\u2009years [IQR 1.9\u20136.6]), HZ was not associated with an increased risk of incident PD overall (adjusted HR 0.95, 95% CI 0.90\u20131.01) or in any sensitivity analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found no evidence that HZ was associated with increased risk of incident PD in this cohort. \u00a9 2024 The Authors. <jats:italic>Movement Disorders<\/jats:italic> published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.29701","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T04:05:33Z","timestamp":1705377933000},"page":"438-444","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Herpes Zoster and Risk of Incident Parkinson's Disease in <scp>US<\/scp> Veterans: A Matched Cohort Study"],"prefix":"10.1002","volume":"39","author":[{"given":"Louis","family":"Tunnicliffe","sequence":"first","affiliation":[{"name":"Faculty of Epidemiology &amp; Population Health London School of Hygiene &amp; Tropical Medicine  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5092-6325","authenticated-orcid":false,"given":"Rimona S.","family":"Weil","sequence":"additional","affiliation":[{"name":"Institute of Neurology, University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Breuer","sequence":"additional","affiliation":[{"name":"Department of Infection, Immunity and Inflammation UCL Great Ormond Street Institute of Child Health, University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Rodriguez\u2010Barradas","sequence":"additional","affiliation":[{"name":"Infectious Diseases Section, Department of Medicine, Michael E. DeBakey VAMC Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liam","family":"Smeeth","sequence":"additional","affiliation":[{"name":"Faculty of Epidemiology &amp; Population Health London School of Hygiene &amp; Tropical Medicine  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher T.","family":"Rentsch","sequence":"additional","affiliation":[{"name":"Faculty of Epidemiology &amp; Population Health London School of Hygiene &amp; Tropical Medicine  London UK"},{"name":"Department of Internal Medicine Yale School of Medicine  New Haven Connecticut USA"},{"name":"VA Connecticut Healthcare System, Department of Veterans Affairs  West Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4524-3180","authenticated-orcid":false,"given":"Charlotte","family":"Warren\u2010Gash","sequence":"additional","affiliation":[{"name":"Faculty of Epidemiology &amp; Population Health London School of Hygiene &amp; Tropical Medicine  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.952161"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2010.135"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30287-X"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2015.12.008"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.1549"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2021.3895"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2022.12.029"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1004092"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852919001664"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006075"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000512874"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.4243"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19687"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2014.08.018"},{"issue":"7","key":"e_1_2_9_16_1","first-page":"e660","article-title":"Incident herpes zoster and risk of dementia: a population\u2010based Danish cohort study","volume":"99","author":"Johannesdottir Schmidt SA","year":"2022","journal-title":"Neurology"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14795"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51525"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-020-01157-4"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/15333175211006504"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.16m11312"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0188490"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-202279"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1906466117"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1159\/000477990"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2016.04.006"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22283"},{"issue":"10","key":"e_1_2_9_28_1","first-page":"597","article-title":"Implementation of evidence\u2010based alcohol screening in the veterans health administration","volume":"12","author":"Bradley KA","year":"2006","journal-title":"Am J Manag Care"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.29701","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:23:30Z","timestamp":1760952210000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.29701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,16]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1002\/mds.29701"],"URL":"https:\/\/doi.org\/10.1002\/mds.29701","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,16]]},"assertion":[{"value":"2023-07-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}