{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T07:28:57Z","timestamp":1782804537142,"version":"3.54.5"},"reference-count":12,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:00:00Z","timestamp":1727136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["91218013"],"award-info":[{"award-number":["91218013"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013427","name":"Samenwerkingsverband Noord-Nederland","doi-asserted-by":"publisher","award":["01492947"],"award-info":[{"award-number":["01492947"]}],"id":[{"id":"10.13039\/501100013427","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Myoclonus is characterized by involuntary, shock\u2010like movements, of which cortical (CM) and non\u2010cortical myoclonus (NCM) are most common. Electrophysiology can help differentiate between these subtypes; however, the diagnostic value of several features is largely unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to determine the diagnostic value of the burst duration in distinguishing CM and NCM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We manually identified the burst duration of 8 patients with CM, confirmed by electromyography\u2013electroencephalography registration or somatosensory\u2010evoked potentials, and 19 patients with NCM, suspected due to a myoclonus\u2010dystonia phenotype (MYC\/DYT\u2010<jats:italic>SGCE<\/jats:italic> positive and negative).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sensitivity and specificity were calculated to assess the diagnostic value. The burst duration of CM (31.1\u2009ms) was significantly shorter than that of NCM (56.7\u2009ms), with a sensitivity of 100% and a specificity of 89.5% at a threshold of 45.0\u2009ms. A minimum of 10 randomly selected bursts were sufficient for reliable diagnostic accuracy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The burst duration seems a valuable supportive diagnostic criterion for distinguishing CM and NCM.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.29990","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T03:15:46Z","timestamp":1727147746000},"page":"2275-2280","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Substantiating the Short Burst Duration in Cortical Myoclonus"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0698-2087","authenticated-orcid":false,"given":"Sterre","family":"van der Veen","sequence":"first","affiliation":[{"name":"Department of Neurology University of Groningen, University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Expertise Centre Movement Disorders Groningen University Medical Centre Groningen (UMCG)  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber","family":"Maliepaard","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Groningen, University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Expertise Centre Movement Disorders Groningen University Medical Centre Groningen (UMCG)  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9497-2019","authenticated-orcid":false,"given":"Madelein","family":"van der Stouwe","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Groningen, University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Expertise Centre Movement Disorders Groningen University Medical Centre Groningen (UMCG)  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelle","family":"Dalenberg","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Groningen, University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Expertise Centre Movement Disorders Groningen University Medical Centre Groningen (UMCG)  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inge","family":"Tuitert","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Groningen, University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Expertise Centre Movement Disorders Groningen University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Academy of Healthcare  Leeuwarden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Willem J.","family":"Elting","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Groningen, University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Expertise Centre Movement Disorders Groningen University Medical Centre Groningen (UMCG)  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5783-571X","authenticated-orcid":false,"given":"Marina A.J.","family":"Tijssen","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Groningen, University Medical Centre Groningen (UMCG)  Groningen The Netherlands"},{"name":"Expertise Centre Movement Disorders Groningen University Medical Centre Groningen (UMCG)  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnp.2022.09.003"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2016.10.093"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2015.198"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000004996"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PARKRELDIS.2021.07.033"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.14802\/jmd.19064"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.CON.0000436156.54532.1a"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-055068"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22273"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000297516.98574.c0"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.9.1.5"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0023-6"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.29990","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:13:05Z","timestamp":1760951585000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.29990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,24]]},"references-count":12,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/mds.29990"],"URL":"https:\/\/doi.org\/10.1002\/mds.29990","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,24]]},"assertion":[{"value":"2024-03-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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