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Understanding their longitudinal stability is essential for successful clinical implementation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to analyze the long\u2010term dynamics of beta peak parameters and beta power distribution along electrodes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We recorded local field potentials from 12 channels per hemisphere of 33 PD patients at rest, in a therapy\u2010off state at two to four sessions (0, 3, 12, 18\u201344\u2009months) post\u2010surgery. We analyzed bipolar beta power (13\u201335\u2009Hz) and estimated monopolar beta power in subgroups with consistent recordings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the initial 3 months, beta peak power increased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). While detection of high\u2010beta peaks was more consistent, low\u2010 and high\u2010beta peak frequencies shifted substantially in some hemispheres during all periods. Spatial distribution of beta power correlated over time. Maximal beta power across segmented contact levels and directions was significantly stable compared with chance and increased in stability over time. Active contacts for therapeutic stimulation showed consistently higher normalized beta power than inactive contacts (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings indicate that beta power is a stable chronic biomarker usable for beta\u2010guided programming. For adaptive stimulation, high\u2010beta peaks might be more reliable over time. Greater stability of beta power, center frequency, and spatial distribution beyond an initial stabilization period suggests that the microlesional effect significantly impacts neuronal oscillations, which should be considered in routine clinical practice when using beta activity for automated programming algorithms. \u00a9 2025 The Author(s). <jats:italic>Movement Disorders<\/jats:italic> published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.30169","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T04:55:46Z","timestamp":1742273746000},"page":"1070-1084","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Long\u2010Term Stability of Spatial Distribution and Peak Dynamics of Subthalamic Beta Power in Parkinson's Disease Patients"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8809-8481","authenticated-orcid":false,"given":"Jennifer K.","family":"Behnke","sequence":"first","affiliation":[{"name":"Movement Disorders and Neuromodulation Unit, Department of Neurology Charit\u00e9 University Medicine  Berlin Germany"},{"name":"Berlin Institute of Health (BIH)  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8738-5825","authenticated-orcid":false,"given":"Robert L.","family":"Peach","sequence":"additional","affiliation":[{"name":"Department of Brain Sciences Imperial College London  London UK"},{"name":"UK Dementia Research Institute Imperial College London  London UK"},{"name":"Department of Neurology University Hospital W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen G.V.","family":"Habets","sequence":"additional","affiliation":[{"name":"Movement 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2814-3532","authenticated-orcid":false,"given":"Jan","family":"Roediger","sequence":"additional","affiliation":[{"name":"Movement Disorders and Neuromodulation Unit, Department of Neurology Charit\u00e9 University Medicine  Berlin Germany"},{"name":"Berlin Institute of Health (BIH)  Berlin Germany"},{"name":"Einstein Center for Neurosciences Berlin  Berlin Germany"},{"name":"NeuroCure Clinical Research Centre Charit\u00e9 University Medicine  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varvara","family":"Mathiopoulou","sequence":"additional","affiliation":[{"name":"Movement Disorders and Neuromodulation Unit, Department of Neurology Charit\u00e9 University Medicine  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1290-208X","authenticated-orcid":false,"given":"Lucia 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