{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:00:07Z","timestamp":1790190007459,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T00:00:00Z","timestamp":1742428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The burden of non\u2010motor symptoms in Parkinson's disease (PD) can be measured with the Non\u2010Motor Symptoms Scale (NMSS) and the International Parkinson and Movement Disorder Society Non\u2010Motor Rating Scale (MDS\u2010NMS), for which scoring systems, structure and clinical coverage differ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The goal was to develop conversion formulas between the NMSS and the MDS\u2010NMS scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 402 patients with PD participating in the primary MDS\u2010NMS validation study were used. The association between domain and total scores of both scales was assessed by the Spearman rank correlation coefficient and Kendall's <jats:italic>W<\/jats:italic> concordance coefficient. Equations for between\u2010scale transformation of total score were constructed from weighted linear regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Spearman rank correlations showed that MDS\u2010NMS domains correlated 0.39 to 0.88 with the corresponding NMSS domains. The equation for transforming the NMSS total score to MDS\u2010NMS total score is: MDS\u2010NMS\u2009=\u200911.629 + 1.624\u2009\u00d7\u2009NMSS (<jats:italic>P<\/jats:italic> &lt;\u20090.001, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> =\u20090.748). For converting the MDS\u2010NMS total score to NMSS total score, the formula is NMSS\u2009=\u20092.475 + 0.495\u2009\u00d7\u2009MDS\u2010NMS (<jats:italic>P<\/jats:italic> &lt;\u20090.001, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> =\u20090.771).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our conversion equations enable direct comparison of the NMSS and MDS\u2010NMS instruments, facilitating data comparability across studies. \u00a9 2025 International Parkinson and Movement Disorder Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mds.30172","type":"journal-article","created":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T08:37:53Z","timestamp":1742459873000},"page":"813-820","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Conversion between <scp>NMSS<\/scp> and <scp>MDS<\/scp>\u2010<scp>NMS<\/scp> in Parkinson's Disease"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4945-5498","authenticated-orcid":false,"given":"Michela","family":"Garon","sequence":"first","affiliation":[{"name":"Padua Neuroscience Center (PNC) University of Padua  Padua Italy"},{"name":"Parkinson's Disease and Movement Disorders Unit, Center for Rare Neurological Diseases (ERN\u2010RND), Department of Neurosciences University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9\u2010Manuel","family":"Rojo\u2010Albuin","sequence":"additional","affiliation":[{"name":"Department of Statistics, Center of Human and Social Sciences Spanish Council for Scientific Research  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2815-0505","authenticated-orcid":false,"given":"K. Ray","family":"Chaudhuri","sequence":"additional","affiliation":[{"name":"Department of Basic and Clinical Neuroscience Institute of Psychiatry, Psychology and Neuroscience, King's College London  London United Kingdom"},{"name":"Parkinson's Foundation Centre of Excellence King's College Hospital NHS Foundation Trust  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0935-9111","authenticated-orcid":false,"given":"Alexandra","family":"Rizos","sequence":"additional","affiliation":[{"name":"King's College Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3829-0675","authenticated-orcid":false,"given":"Carmen","family":"Rodriguez\u2010Blazquez","sequence":"additional","affiliation":[{"name":"National Center of Epidemiology and CIBERNED Carlos III Institute of Health  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7414-9480","authenticated-orcid":false,"given":"Eugenia","family":"Mamikonyan","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5846-755X","authenticated-orcid":false,"given":"Roberta","family":"Biundo","sequence":"additional","affiliation":[{"name":"Department of General Psychology University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9872-6680","authenticated-orcid":false,"given":"Anette","family":"Schrag","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurosciences UCL Institute of Neurology, University College London  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0633-7168","authenticated-orcid":false,"given":"Daniel","family":"Weintraub","sequence":"additional","affiliation":[{"name":"Education and Clinical Centers, Philadelphia Veterans Affairs Medical Center Philadelphia University of Pennsylvania and the Parkinsons Disease and Mental Illness Research  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1040-2807","authenticated-orcid":false,"given":"Angelo","family":"Antonini","sequence":"additional","affiliation":[{"name":"Padua Neuroscience Center (PNC) University of Padua  Padua Italy"},{"name":"Parkinson's Disease and Movement Disorders Unit, Center for Rare Neurological Diseases (ERN\u2010RND), Department of Neurosciences University of Padova  Padova Italy"},{"name":"Parkinson and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE), Department 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