{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:58:12Z","timestamp":1792803492317,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008440","name":"International Parkinson and Movement Disorder Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Movement Disorder Society Non\u2010Motor Rating Scale (MDS\u2010NMS) assesses severity and frequency of non\u2010motor symptoms (NMS) in Parkinson's disease (PD) and is rater\u2010administered. The MDS\u2010NMS Questionnaire (MDS\u2010NMS\u2010Q), developed as a briefer (i.e., assessing symptom severity only), self\u2010completed version of the MDS\u2010NMS, is also a 13\u2010domain, 52\u2010symptom instrument with a separate non\u2010motor fluctuations (NMFs) section.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The goal was to validate the MDS\u2010NMS\u2010Q versus the MDS\u2010NMS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional, multi\u2010site, international study was conducted with idiopathic PD patients. After completing the self\u2010administered MDS\u2010NMS\u2010Q unsupervised, patients were assessed with the rater\u2010administered MDS\u2010NMS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The cohort consisted of 199 PD patients (mean age [\u00b1standard deviation (SD)]\u2009=\u200967.19 [\u00b19.95] years; mean age at PD diagnosis [\u00b1SD]\u2009=\u200959.27 [\u00b19.54] years); median Hoehn and Yahr stage\u2009=\u20092. Data quality was satisfactory for all 13 MDS\u2010NMS\u2010Q domains. There were no floor or ceiling effects for the total score; individual domains had no appreciable ceiling effects, but variable floor effects (5.0%\u201371.4%). Internal consistency for most domains was satisfactory, except for the impulse control domain (Cronbach's \u03b1 \u22650.75 for 10\/13 domains). Correlation and concordance between MDS\u2010NMS\u2010Q and MDS\u2010NMS total scores were high (Spearman rank correlation coefficient\u2009=\u20090.86; Kendall's coefficient of concordance\u2009=\u20090.93).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The MDS\u2010NMS\u2010Q has a strong association and concordance with the MDS\u2010NMS at the total score and domain level. This indicates that the MDS\u2010NMS\u2010Q, allowing self\u2010completion and focusing only on symptom severity, is an acceptable alternative to rater administration assessing both severity and frequency. \u00a9 2025 International Parkinson and Movement Disorder Society.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.30202","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T21:29:21Z","timestamp":1745011761000},"page":"1037-1046","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Validation of the International Parkinson and Movement Disorder Society Non\u2010Motor Symptoms Questionnaire (\n                    <scp>MDS<\/scp>\n                    \u2010\n                    <scp>NMS<\/scp>\n                    \u2010Q)"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0633-7168","authenticated-orcid":false,"given":"Daniel","family":"Weintraub","sequence":"first","affiliation":[{"name":"Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania  Philadelphia Pennsylvania USA"},{"name":"Parkinson's Disease Research, Education and Clinical Ctr. (PADRECC), Corporal Michael J. Crescenz Veterans Affairs Medical Center  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kallol Ray","family":"Chaudhuri","sequence":"additional","affiliation":[{"name":"Parkinson's Foundation Ctr. of Excellence, King's College Hospital and King's College London  London United Kingdom"},{"name":"Visiting Neurologist and Professor, Kings College Hospital  Dubai United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9872-6680","authenticated-orcid":false,"given":"Anette","family":"Schrag","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Martinez\u2010Martin","sequence":"additional","affiliation":[{"name":"Center for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED) Carlos III Institute of Health  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Rizos","sequence":"additional","affiliation":[{"name":"Parkinson's Foundation Ctr. of Excellence, King's College Hospital and King's College London  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia","family":"Mamikonyan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabelle","family":"Schoen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliet","family":"Staunton","sequence":"additional","affiliation":[{"name":"Parkinson's Foundation Ctr. of Excellence, King's College Hospital and King's College London  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta Pereira","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Royal Free London NHS Foundation Trust  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3829-0675","authenticated-orcid":false,"given":"Carmen","family":"Rodriguez\u2010Blazquez","sequence":"additional","affiliation":[{"name":"Center for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED) Carlos III Institute of Health  Madrid Spain"},{"name":"National Centre of Epidemiology Carlos III Institute of Health  Madrid 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