{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T18:17:27Z","timestamp":1789237047799,"version":"build-2803163510"},"reference-count":65,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hearing loss is increasingly recognized as a non\u2010motor manifestation of Parkinson's disease (PD), but its prevalence, characteristics, and underlying mechanisms remain unclear. This systematic review aims to evaluate the prevalence and characteristics of hearing loss in people with PD (PwPD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, Embase, and Web of Science were searched without restrictions. Observational studies assessing hearing loss in PwPD using pure tone audiometry (PTA), speech audiometry (SA), or central auditory processing (CAP) tests were included. Random\u2010effects models were applied, and heterogeneity was examined by meta\u2010regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty\u2010five studies encompassing 1316 PwPD and 820 controls were included. Pooled prevalence indicated 73.9% (95% CI: 61.5%, 84.8%) of 1009 PwPD had hearing loss, with high\u2010frequency impairment (82.6%) more common than low\u2010frequency loss (45.1%). Compared with age matched controls, PwPD were 1.82 times more likely to experience hearing loss (odds ratio\u2009=\u20091.82; 95% CI: 1.19\u20132.78; PwPD\u2009=\u2009599; healthy controls\u2009=\u2009579). Older age and higher\u2010frequency testing predicted higher prevalence. SA results were inconsistent. CAP meta\u2010analyses revealed significant prolongation of brain stem auditory\u2010evoked potential wave III latency (standardized mean difference [SMD]\u2009=\u20090.51; 95% CI: 0.15\u20130.88), wave V latency (SMD\u2009=\u20090.73; 95% CI: 0.25\u20131.21), and I\u2013V interpeak interval (SMD\u2009=\u20090.84; 95% CI: 0.41\u20131.27). Among late latency potentials, N200 latency (SMD\u2009=\u20090.60; 95% CI: 0.20\u20130.99) and P300 latency (SMD\u2009=\u20090.73; 95% CI: 0.49\u20130.98) were significantly delayed, while other components showed no group differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hearing loss is common in PD, extending beyond age\u2010related decline and likely involving both peripheral and central pathways. It may represent an early non\u2010motor symptom and a marker of cognitive vulnerability. \u00a9 2026 International Parkinson and Movement Disorder Society.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.70206","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T05:51:00Z","timestamp":1769838660000},"page":"1069-1080","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hearing Loss in Parkinson's Disease: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6511-4103","authenticated-orcid":false,"given":"Shahryar","family":"Rajai Firouzabadi","sequence":"first","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0662-0329","authenticated-orcid":false,"given":"Ida","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6411-8938","authenticated-orcid":false,"given":"Hossein","family":"Golsorkh","sequence":"additional","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajjad","family":"Mahdavi","sequence":"additional","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6562-8876","authenticated-orcid":false,"given":"Sara","family":"Sadeghzadeh","sequence":"additional","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0451-3175","authenticated-orcid":false,"given":"Kamran","family":"Rezaei","sequence":"additional","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1675-681X","authenticated-orcid":false,"given":"Mehri","family":"Salari","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/ejo.ejo_18_18"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1044\/2019_JSLHR-H-19-0097"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1044\/2020_JSLHR-20-00594"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-015-1405-5"},{"key":"e_1_2_9_6_1","article-title":"A non\u2010motor symptom unheard of? 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