{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:45:06Z","timestamp":1791945906742,"version":"4.3.4"},"reference-count":145,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Adaptive deep brain stimulation (aDBS) represents an important evolution in the treatment of Parkinson's disease (PD), building on conventional DBS (cDBS) by adjusting stimulation in response to real\u2010time physiological signals. By enabling dynamic targeting of disease\u2010related neural activity, aDBS offers the potential for more precise modulation of motor symptoms. Additional anticipated advantages include reduced stimulation\u2010related side effects and improved energy efficiency, supporting long\u2010term device performance. Although clinical uptake is still at an early stage, growing experience has highlighted both opportunities and areas requiring further refinement. Key challenges include inter\u2010individual variability in biomarker expression, diversity in programming approaches, and ongoing debate regarding optimal thresholds and response latencies. The clinical significance of short\u2010term local field potential (LFP) recordings continues to be actively investigated, particularly in the context of signal artifacts, physiological variability, and current hardware limitations. Beyond technical considerations, factors such as patient selection, ethical frameworks, and cost\u2010effectiveness remain important determinants of broader implementation. Continued progress will depend on the development of robust and flexible control strategies that incorporate multimodal biomarkers, including wearable\u2010derived motor metrics and patient\u2010reported outcomes, to support personalized therapy. With an expanding evidence base and recent regulatory approvals, aDBS is increasingly transitioning from an experimental concept to a viable clinical tool. Future efforts should prioritize the translation of research paradigms into scalable clinical workflows that effectively balance automation with individualized patient care. \u00a9 2026 The Author(s).\n                    <jats:italic>Movement Disorders<\/jats:italic>\n                    published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.\n                  <\/jats:p>","DOI":"10.1002\/mds.70284","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:05:12Z","timestamp":1775041512000},"page":"1370-1383","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Adaptive\n                    <scp>Deep Brain Stimulation<\/scp>\n                    for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation"],"prefix":"10.1002","volume":"41","author":[{"given":"Thomas","family":"Koeglsperger","sequence":"first","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)  Munich Germany"},{"name":"Department of Neurology LMU University Hospital, LMU Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5280-2828","authenticated-orcid":false,"given":"Maximilian","family":"Scherer","sequence":"additional","affiliation":[{"name":"Department of Neurology LMU University Hospital, LMU Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea A.","family":"K\u00fchn","sequence":"additional","affiliation":[{"name":"Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin  Berlin Germany"},{"name":"Bernstein Center for Computational Neuroscience Humboldt Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Exzellenzcluster NeuroCure Charit\u00e9 \u2010 Universit\u00e4tsmedizin Berlin  Berlin Germany"},{"name":"Berlin School of Mind and Brain Humboldt \u2010 Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"German Center for Neurodegenerative Diseases (DZNE)  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Eusebio","sequence":"additional","affiliation":[{"name":"APHM, Department of Neurology and Movement Disorders Timone University Hospital  Marseille France"},{"name":"Aix\u2010 Marseille University Institut de Neurosciences de la Timone, UMR 7289 CNRS\u2010AMU  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5346-0180","authenticated-orcid":false,"given":"Alfonso","family":"Fasano","sequence":"additional","affiliation":[{"name":"Edmond J Safra Program in Parkinson's disease and Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, UHN and Division of Neurology University of Toronto  Toronto Ontario Canada"},{"name":"Krembil Brain Institute  Toronto Ontario Canada"},{"name":"Department of Biomedical Sciences Humanitas University  Milan Italy"},{"name":"IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim K.","family":"Krauss","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Hannover Medical School  Hannover Germany"},{"name":"Center for Systems Neuroscience  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa060281"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-025-12915-6"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-018-0128-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00410"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00314"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-020-00426-z"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-022-00396-7"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.09.022"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.01.014"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-00974-5"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2009.06.011"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-017-0083-7"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29052"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29415"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-022-00301-2"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2022.113977"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2020.09.027"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-021-00229-z"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-022-11495-z"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-01124-7"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2025.2781"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28513"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25078"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg267"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3171\/2018.5.focus18155"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2021.113825"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-57071-5"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-024-03125-0"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0000000000005121"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26953"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2015-310972"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23951"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2020.07.016"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1109\/embc.2018.8513348"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2019.02.020"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.21-03-01033.2001"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.04717.x"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awx252"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2012.00155"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2012.06.012"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.1128-16.2016"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awaa297"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/aabc9b"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26759"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2012.06650.x"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awab264"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2019.104605"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1109\/embc.2018.8512741"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.1975-19.2019"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awz141"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2021.105287"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28625"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.748165"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2007.12.001"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2005.02.010"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2017.08.028"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2007.05.004"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23594"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27418"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26860"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2010.217489"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.0282-08.2008"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00564"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.7554\/elife.31895"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2011.02.015"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.0767-12.2012"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.30160"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-58132-7"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-024-03196-z"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.2313-20.2021"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2017.11.071"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2023.08.026"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.5459-09.2010"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2016.01.015"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27800"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-00943-y"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/jsan14020023"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2021.01.023"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-61789-3"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/ac86a2"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aww286"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-022-01932-x"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.adc9669"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-023-00905-9"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.26835"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.734186"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.732499"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1159\/000521431"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2021.08.016"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-022-00350-7"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/ac59a3"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awx010"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.70311"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0000000000204762"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0000000000203099"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-024-00772-5"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2015.10.006"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2025.3373"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40120-022-00435-8"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(22)00400-8"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2025.107785"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2022.114150"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.3171\/2021.3.jns204113"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2016.10.095"},{"key":"e_1_2_9_106_1","doi-asserted-by":"crossref","unstructured":"SchererM WiedemannN BoetzelK et al.Inconsistent Subthalamic Beta Expression in the Local Field Potential amid In\u2010 and Anti\u2010Phasic Neuronal Bursts;2025.https:\/\/doi.org\/10.64898\/2025.12.16.694607.","DOI":"10.64898\/2025.12.16.694607"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2009.12.013"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/abfc1c"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2024.1370287"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2025.08.002"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.70042"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51463"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.30169"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2024.106589"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.725797"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-022-11388-1"},{"key":"e_1_2_9_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2025.105988"},{"key":"e_1_2_9_118_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.30212"},{"key":"e_1_2_9_119_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2001560117"},{"key":"e_1_2_9_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2021.105372"},{"key":"e_1_2_9_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2589-7500(22)00214-x"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2025.03.008"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.561323"},{"key":"e_1_2_9_124_1","doi-asserted-by":"crossref","unstructured":"PeschkeS DongJ KirschnerA et al.Patient Reported Feedback Suggests an Alternative Sweet Spot for DBS Programming in Essential Tremor;2025.https:\/\/doi.org\/10.21203\/rs.3.rs-8050162\/v1.","DOI":"10.21203\/rs.3.rs-8050162\/v1"},{"key":"e_1_2_9_125_1","doi-asserted-by":"crossref","unstructured":"OffJ SchererM PeschkeS et al.Psychometric reliability of patient\u2010reported visual analogue scales in STN\u2010DBS programming for Parkinson's disease;2025.https:\/\/doi.org\/10.21203\/rs.3.rs-8047862\/v1.","DOI":"10.21203\/rs.3.rs-8047862\/v1"},{"key":"e_1_2_9_126_1","first-page":"249","volume-title":"Handb Clin Neurol","author":"Lofredi R","year":"2022"},{"key":"e_1_2_9_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2021.09.002"},{"key":"e_1_2_9_128_1","doi-asserted-by":"publisher","DOI":"10.7554\/elife.75126"},{"key":"e_1_2_9_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-025-01438-0"},{"key":"e_1_2_9_130_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26858"},{"key":"e_1_2_9_131_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-025-13000-8"},{"key":"e_1_2_9_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-00990-5"},{"key":"e_1_2_9_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2014.252"},{"key":"e_1_2_9_134_1","doi-asserted-by":"publisher","DOI":"10.1159\/000343202"},{"key":"e_1_2_9_135_1","doi-asserted-by":"publisher","DOI":"10.3171\/2018.4.jns172995"},{"key":"e_1_2_9_136_1","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcaf266"},{"key":"e_1_2_9_137_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0000000000001334"},{"key":"e_1_2_9_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2023.08.017"},{"key":"e_1_2_9_139_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.4676-12.2013"},{"key":"e_1_2_9_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-01011-1"},{"key":"e_1_2_9_141_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.2208-16.2017"},{"key":"e_1_2_9_142_1","doi-asserted-by":"publisher","DOI":"10.1101\/2025.03.11.642600"},{"key":"e_1_2_9_143_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-024-00639-9"},{"key":"e_1_2_9_144_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-025-01131-5"},{"key":"e_1_2_9_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-022-00443-3"},{"key":"e_1_2_9_146_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.70076"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.70284","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mds.70284","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.70284","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:02:28Z","timestamp":1791943348000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.70284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":145,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/mds.70284"],"URL":"https:\/\/doi.org\/10.1002\/mds.70284","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,1]]},"assertion":[{"value":"2026-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}