{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:46:48Z","timestamp":1792597608044,"version":"4.5.0"},"reference-count":42,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Finely tuned Gamma (FTG) activity\u2014spontaneous narrowband Gamma oscillations (sFTG) or entrained to half the stimulation frequency (eFTG)\u2014is typically linked to on\u2010medication states and dyskinesia in Parkinson's disease (PD), making it a potential physiomarker for adaptive deep brain stimulation (aDBS). However, its characteristics and determinants remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This exploratory study examined FTG prevalence, clinical correlates, and associations with DBS parameters, to guide future prospective work.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Local field potentials recorded in the subthalamic nucleus (STN) of PD patients with Percept neurostimulator were retrospectively analyzed, based on a predefined set of clinically relevant questions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 67 patients (134 STNs), sFTG occurred in 19% of STNs, and 1:2 eFTG in 28%. FTG was always associated with a medication, stimulation, or a stun\u2010effect induced ON\u2010state or a combination thereof, but could occur independent of dyskinesia. sFTG was most often observed during the transition from \u03b2 to eFTG (54%), and rarely co\u2010occurred shortly with eFTG (19%). \u03b2 activity often co\u2010occurred with FTG (50%), showing an inverse power relation with 1:2 eFTG. The occurrence of 1:2 eFTG depended on stimulation amplitudes. In 12 STN (9%), subharmonic artifacts occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      FTG seems to be associated with an overall ON\u2010state, independent of dyskinesia. The ratio 1:2 eFTG likely reflects entrainment of the neural populations underlying sFTG, but can occur without prior occurrence of sFTG, depending on stimulation amplitude consistent with \u201cArnold's tongue\u201d framework. Future research should further specify \u03b2 and FTG subtype interactions, while accounting for artifacts. Combining these physiomarkers may improve aDBS algorithms. \u00a9 2026 The Author(s).\n                      <jats:italic>Movement Disorders<\/jats:italic>\n                      published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.70419","type":"journal-article","created":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T03:50:44Z","timestamp":1784346644000},"page":"2677-2687","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Decoding Finely Tuned Gamma Oscillations in Chronic Deep Brain Stimulation for Parkinson's Disease"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0944-8069","authenticated-orcid":false,"given":"Marjolein","family":"Muller","sequence":"first","affiliation":[{"name":"Department of Neurology Leiden University Medical Center  Leiden The Netherlands"},{"name":"Department of Neurology Haga Teaching Hospital  The Hague The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eline Anna Maria Yolanda","family":"Rouleau","sequence":"additional","affiliation":[{"name":"Department of Neurology Leiden University Medical Center  Leiden The Netherlands"},{"name":"Department of Neurology Haga Teaching Hospital  The Hague The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saskia","family":"van der Gaag","sequence":"additional","affiliation":[{"name":"Department of Neurology Haga Teaching Hospital  The Hague The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodi","family":"Zutt","sequence":"additional","affiliation":[{"name":"Department of Neurology Haga Teaching Hospital  The Hague The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carel Frederik 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