{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:43:58Z","timestamp":1792813438341,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disorders"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Remote programming of deep brain stimulation may improve access to specialized postoperative care for people with Parkinson's disease, but prospective randomized evidence remains limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to determine whether remote follow\u2010up programming after standardized inpatient initiation is noninferior to conventional in\u2010person follow\u2010up programming for motor outcomes during the early postoperative period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this prospective, randomized, open\u2010label, multicenter noninferiority trial, adults with idiopathic Parkinson's disease who recently underwent bilateral subthalamic nucleus deep brain stimulation implantation at six German centers were randomly assigned 1:1 to conventional in\u2010person follow\u2010up programming or remote follow\u2010up programming through a secure telemedicine platform during the first 90\u2009days after surgery. All participants underwent initial in\u2010person postoperative programming before randomization. The primary outcome was the Movement Disorder Society\u2013Unified Parkinson's Disease Rating Scale Part III score at 90\u2009days in the medication\n                      <jats:italic>on<\/jats:italic>\n                      and stimulation ON state. The prespecified noninferiority margin was 5 points.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty\u2010two participants were randomly assigned. The per\u2010protocol population included 26 participants in the conventional care group and 22 in the remote programming group. The between\u2010group median difference of the primary endpoint was \u22122.5 points (95% confidence interval, \u22129.0 to 2.0), meeting the prespecified noninferiority criterion. Secondary clinical outcomes and patient\u2010reported outcomes were broadly comparable between groups. Serious adverse events occurred at similar frequencies in both groups, and no deaths occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Remote follow\u2010up programming after standardized inpatient initiation achieved motor outcomes noninferior to conventional in\u2010person follow\u2010up during the first 3\u2009months, with no clear short\u2010term safety signal. \u00a9 2026 The Author(s).\n                      <jats:italic>Movement Disorders<\/jats:italic>\n                      published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mds.70575","type":"journal-article","created":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:28:16Z","timestamp":1792812496000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Remote Versus In\u2010Person Follow\u2010up Programming After Subthalamic Deep Brain Stimulation for Parkinson's Disease: A Multicenter Randomized Noninferiority Trial"],"prefix":"10.1002","author":[{"given":"Juhi","family":"Shaik","sequence":"first","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Zentsch","sequence":"additional","affiliation":[{"name":"Department of Neurology University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8540-3789","authenticated-orcid":false,"given":"Carsten","family":"Buhmann","sequence":"additional","affiliation":[{"name":"Department of Neurology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8016-1821","authenticated-orcid":false,"given":"Ute","family":"Hidding","sequence":"additional","affiliation":[{"name":"Department of Neurology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4888-543X","authenticated-orcid":false,"given":"Thomas M.","family":"Kinfe","sequence":"additional","affiliation":[{"name":"Division of Functional Neurosurgery and Stereotaxy, Department of Neurosurgery Friedrich\u2010Alexander Universit\u00e4t (FAU) Erlangen\u2010N\u00fcrnberg  Erlangen Germany"},{"name":"Mannheim Center for Neuromodulation and Neuroprosthetics, Department of Neurosurgery, Medical Faculty Mannheim Heidelberg University  Mannheim Germany"},{"name":"Mannheim Center for Translational Neuroscience, Medical Faculty Mannheim Heidelberg University  Mannheim Germany"},{"name":"Mannheim Comprehensive Medical Systems Technology Campus, Medical Faculty Mannheim Heidelberg University  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2172-7386","authenticated-orcid":false,"given":"Martin","family":"Regensburger","sequence":"additional","affiliation":[{"name":"Department of Molecular Neurology Friedrich\u2010Alexander Universit\u00e4t of Erlangen\u2010N\u00fcrnberg  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7357-713X","authenticated-orcid":false,"given":"Jost\u2010Julian","family":"Rumpf","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6414-7939","authenticated-orcid":false,"given":"Alfons","family":"Schnitzler","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical Faculty, Institute of Clinical Neuroscience and Medical Psychology Heinrich Heine University  D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5744-5981","authenticated-orcid":false,"given":"Jing","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Scherer","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7582-2215","authenticated-orcid":false,"given":"Elisabeth","family":"Kaufmann","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5092-4306","authenticated-orcid":false,"given":"Johannes","family":"Levin","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"},{"name":"German Center for Neurodegenerative Diseases  Munich Germany"},{"name":"Munich Cluster for Systems Neurology (SyNergy)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Crispin","sequence":"additional","affiliation":[{"name":"Institute of Medical Data Processing, Biometry and Epidemiology, Pettenkofer School of Public Health, Faculty of Medicine, LMU Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7587-6187","authenticated-orcid":false,"given":"G\u00fcnter","family":"H\u00f6glinger","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"},{"name":"German Center for Neurodegenerative Diseases  Munich Germany"},{"name":"Munich Cluster for Systems Neurology (SyNergy)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan H.","family":"Mehrkens","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery LMU University Hospital, LMU Medizin  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6101-0323","authenticated-orcid":false,"given":"Thomas","family":"Koeglsperger","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Medizin Ludwig Maximilian University of Munich  Munich Germany"},{"name":"German Center for Neurodegenerative Diseases  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20961"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20959"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa000827"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/tmj.2021.0117"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25903"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1089\/tmj.2018.0101"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/cpj.0000000000000252"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28098"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-10273-z"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.12.030"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3171\/2021.8.focus21383"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1398929"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.1061274"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.879250"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/20552076241287071"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43856-025-00744-7"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.70228"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcag100"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2025.03.008"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2015.10.006"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa060281"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2026.104070"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-025-02315-5"},{"key":"e_1_2_9_25_1","doi-asserted-by":"crossref","unstructured":"PeschkeS DongJ KirschnerA et al.Patient reported feedback suggests an alternative sweet spot for DBS programming in essential tremor.2025.https:\/\/doi.org\/10.21203\/rs.3.rs-8050162\/v1","DOI":"10.21203\/rs.3.rs-8050162\/v1"},{"key":"e_1_2_9_26_1","doi-asserted-by":"crossref","unstructured":"OffJ SchererM PeschkeS et al.Psychometric reliability of patient\u2010reported visual analogue scales in STN\u2010DBS programming for Parkinson's disease.2025.https:\/\/doi.org\/10.21203\/rs.3.rs-8047862\/v1","DOI":"10.21203\/rs.3.rs-8047862\/v1"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-01128-3"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2024.1378614"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1101\/2023.02.02.23285397"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/3085140"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8492619"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-018-0116-x"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-22206-z"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44360-026-00131-z"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.70575","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mds.70575","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.70575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:28:21Z","timestamp":1792812501000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.70575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,23]]},"references-count":33,"alternative-id":["10.1002\/mds.70575"],"URL":"https:\/\/doi.org\/10.1002\/mds.70575","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,23]]},"assertion":[{"value":"2026-05-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"mds.70575"}}