{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:12:34Z","timestamp":1763035954431,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,10,12]],"date-time":"2004-10-12T00:00:00Z","timestamp":1097539200000},"content-version":"vor","delay-in-days":5033,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[1991,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Age of onset and severity of idiopathic torsion dystonia (ITD) were studied in 100 British families containing 107 index cases and 79 secondary cases. Analysis of variance of these clinical features did not suggest that ITD is genetically heterogenous, and they were similar in Jewish and non\u2010Jewish patients. Intrafamilial correlation for age of onset was low, particularly between parents and their offspring, suggesting that the ITD phenotype may be determined in part by nongenetic factors or an allelic modifying gene.<\/jats:p>","DOI":"10.1002\/mds.870060407","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T18:51:24Z","timestamp":1104519084000},"page":"310-314","source":"Crossref","is-referenced-by-count":9,"title":["Intrafamilial correlation in idiopathic torsion dystonia"],"prefix":"10.1002","volume":"6","author":[{"given":"N. A.","family":"Fletcher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. E.","family":"Harding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. D.","family":"Marsden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/97.1.793"},{"key":"e_1_2_1_3_2","series-title":"Advances in neurology","first-page":"35","volume-title":"Dystania 2","author":"Marsden CD.","year":"1988"},{"key":"e_1_2_1_4_2","first-page":"188","article-title":"Idiopathic torsion dystonia. I. The hereditary pattern","volume":"11","author":"Zeman W","year":"1959","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_5_2","series-title":"Advances in Neurology","first-page":"137","volume-title":"Dystonia","author":"Lee LV","year":"1976"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.20.11_Part_2.1"},{"key":"e_1_2_1_7_2","first-page":"231","volume-title":"Genetic diseases among Ashkenazi Jews","author":"Eldridge R","year":"1979"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.21.1.13"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410260505"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/113.2.379"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02983018"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.1.73"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.2307\/2530491"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1981.tb01052.x"},{"key":"e_1_2_1_15_2","first-page":"78","volume-title":"Statistics for experimentalists","author":"Cooper BE.","year":"1969"},{"issue":"14","key":"e_1_2_1_16_2","first-page":"125","article-title":"The problem of anticipation in pedigrees of dystrophia myotonica","volume":"9","author":"Penrose LS.","year":"1948","journal-title":"Ann Eugen(London)"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(89)90188-8"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270203"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.870060407","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.870060407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:38:02Z","timestamp":1760971082000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.870060407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1991,1]]}},"alternative-id":["10.1002\/mds.870060407"],"URL":"https:\/\/doi.org\/10.1002\/mds.870060407","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[1991,1]]}}}