{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:33:31Z","timestamp":1763746411650,"version":"build-2065373602"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,12]],"date-time":"2004-10-12T00:00:00Z","timestamp":1097539200000},"content-version":"vor","delay-in-days":3937,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[1994,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Botulinum toxin is now an established treatment for blepharospasm, hemifacial spasm, spasmodic torticollis, and spastic dysphonia. We report the effectiveness of botulinum toxin against painful limb myoclonus of spinal cord origin. The patient, a 16\u2010year\u2010old girl with a pulmonary vascular anomaly, Scimitar syndrome, suffered from an acute spinal cord infarct at age 11. She was left with paralysis of the right leg and bladder dysfunction. Four years after the original insult, she developed \u201cpainful cramping\u201d and involuntary movements of the left thigh, which were unresponsive to a wide range of therapeutic trials. The movements were continuous, rhythmic, and confined to the left quadriceps muscles. Electromyographic examination revealed continuous myoclonic discharges. Treatment with botulium toxin in the left quadriceps muscles resulted in complete cessation of pain and marked reduction in amplitude of the movements, both clinically and electromyographically. This observation indicates the efficacy of botulinum toxin in the treatment of painful spinal myoclonus.<\/jats:p>","DOI":"10.1002\/mds.870090221","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T11:35:19Z","timestamp":1104492919000},"page":"233-235","source":"Crossref","is-referenced-by-count":29,"title":["Effectiveness of botulinum toxin type A against painful limb myoclonus of spinal cord origin"],"prefix":"10.1002","volume":"9","author":[{"given":"Kathleen B.","family":"Polo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahman","family":"Jabbari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199104253241707"},{"key":"e_1_2_1_3_2","first-page":"924","article-title":"Pharmacologic weakening of extraocular muscles","volume":"12","author":"Scott AB","year":"1973","journal-title":"Invest Ophthalmol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1985.01050030043017"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880150909"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.8.1213"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.8.633"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410280407"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.65.762.208"},{"key":"e_1_2_1_10_2","first-page":"1185","volume":"41","author":"Jankovic J","year":"1991","journal-title":"Botulinum toxin treatment tremors, Neurology"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.1_Part_1.183"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.3.627"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90296-1"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)91198-D"},{"key":"e_1_2_1_15_2","first-page":"88","article-title":"Myokymia and the benign fasciculation of muscular cramps","volume":"61","author":"Denny\u2010Brown D","year":"1948","journal-title":"Trans Assoc Am Physicians"},{"key":"e_1_2_1_16_2","first-page":"261","article-title":"Cramps, spasms and muscle stiffness","volume":"141","author":"Rowland LP","year":"1985","journal-title":"Rev Neurol"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.37.10.1112"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.10.942"},{"key":"e_1_2_1_19_2","first-page":"197","article-title":"Axial myoclonus of propriospinal origin","volume":"114","author":"Brown P","year":"1991","journal-title":"Brain"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.8.1591"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1159\/000114733"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880141102"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880040606"},{"volume-title":"Electrodiagnosis in diseases of nerve and muscle","year":"1989","author":"Kimura J","key":"e_1_2_1_24_2"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-199110000-00005"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.870090221","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.870090221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:23:52Z","timestamp":1760970232000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.870090221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,1]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1994,1]]}},"alternative-id":["10.1002\/mds.870090221"],"URL":"https:\/\/doi.org\/10.1002\/mds.870090221","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[1994,1]]}}}