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A thorough search for metabolic, toxic, infectious, or degenerative causes of myoclonus was unsuccessful. The presence of intrathecal immune activation in at least a subgroup of patients with the clinical features of progressive myoclonic ataxia suggests the possibility of immune\u2010mediated damage within the central nervous system in this condition.<\/jats:p>","DOI":"10.1002\/mds.870100212","type":"journal-article","created":{"date-parts":[[2005,5,28]],"date-time":"2005-05-28T20:14:51Z","timestamp":1117311291000},"page":"207-210","source":"Crossref","is-referenced-by-count":1,"title":["Intrathecal immune activation in three patients with progressive myoclonic ataxia"],"prefix":"10.1002","volume":"10","author":[{"given":"A.","family":"Salmaggi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Carella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ciano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Binelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Giovannini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Palazzini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Girotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,12]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"196","volume-title":"Movement disorders","author":"Marsden CD","year":"1982"},{"key":"e_1_2_1_3_2","first-page":"436","volume-title":"Disorders of movement. 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