{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T14:08:59Z","timestamp":1786802939628,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,11,4]],"date-time":"2004-11-04T00:00:00Z","timestamp":1099526400000},"content-version":"vor","delay-in-days":2986,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[1996,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report two patients with subacute diffuse encephalopathy characterized by confusion, myoclonic encephalopathy, and mild akineto\u2010rigid extrapyramidal signs in one case and by apathy, memory deficit, and partial complex seizures in the other. Hashimoto's thyroiditis with high titers of antithyroglobulin antibodies was diagnosed in both patients, who were unresponsive to anticonvulsant medication, but showed rapid neurological improvement following steroid treatment. On neuropsychological examination, predominant frontotemporal dysfunction was noted. Electroencephalographic activity was remarkable for its rhythmical delta activity, unresponsive to, or even paradoxically increased by, anticonvulsant treatment. On magnetic resonance imaging, atrophy with temporal predominance was found. These observations support the idea that this potentially treatable dementia and movement disorder should be classified as a separate clinical entity.<\/jats:p>","DOI":"10.1002\/mds.870110511","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T09:47:09Z","timestamp":1104486429000},"page":"555-562","source":"Crossref","is-referenced-by-count":59,"title":["Hashimoto's myoclonic encephalopathy: An underdiagnosed treatable condition?"],"prefix":"10.1002","volume":"11","author":[{"given":"F.","family":"Ghika\u2010Schmid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Ghika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Regli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Dworak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Bogousslavsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"St\u00e4dler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Portmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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Hypoth\u00e8ses pathog\u00e9niques","volume":"141","author":"Latinville D","year":"1985","journal-title":"Rev Neurol"},{"key":"e_1_2_1_9_2","first-page":"371","article-title":"Enc\u00e9phalopathie d'Hashimoto: toxique ou auto\u2010immune","volume":"148","author":"Ghawche F","year":"1992","journal-title":"Rev Neurol"},{"key":"e_1_2_1_10_2","first-page":"147","article-title":"Thyro\u00efdite de Hashimoto et enc\u00e9phalopathie","volume":"23","author":"Mauriac L","year":"1982","journal-title":"Rev Franc Endocrinol Clin"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(86)80121-8"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)92876-5"},{"key":"e_1_2_1_13_2","first-page":"140","article-title":"Hashimoto's encephalopathy: a new neuroimmunological syndrome","volume":"22","author":"Henderson LM","year":"1987","journal-title":"Ann Neurol"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)92875-3"},{"key":"e_1_2_1_15_2","volume-title":"Batterie des Examens Neuropsychologiques du CHUV","author":"Assal G","year":"1985"},{"key":"e_1_2_1_16_2","first-page":"387","article-title":"Principles of albumin and immunoglobulin analyses in neurological disorders. I: establishment of reference values","volume":"1","author":"Tibbling G","year":"1977","journal-title":"Scand J Clin Lab Invest"},{"key":"e_1_2_1_17_2","first-page":"995","article-title":"A case of Hashimoto's encephalopathy with a relapsing course related to menstrual cycle","volume":"33","author":"Ishii K","year":"1993","journal-title":"Rinsho Shinkeigaku"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.5.977"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(82)73397-3"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a069810"},{"key":"e_1_2_1_21_2","first-page":"191","article-title":"Isolated angiitis of the CNS associated with Hashimoto's disease","volume":"32","author":"Shibata N","year":"1992","journal-title":"Rinsho Shinkeigaku"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.870110511","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.870110511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:39:25Z","timestamp":1760953165000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.870110511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,9]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1996,9]]}},"alternative-id":["10.1002\/mds.870110511"],"URL":"https:\/\/doi.org\/10.1002\/mds.870110511","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,9]]}}}