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The latencies of the R1 and R2 components of the blink reflex were not different between the groups. However, in PLMS, the excitability of the R2 response was markedly enhanced: The second R2 response to a pair of stimuli given at an interval of 500 ms was in PLMS 59.5% (range 21\u201387%) of the first R2 response and in controls 18.8% (range 2\u201379%) (p &lt; 0.0001, Mann\u2010Whitney U test). These results provide further evidence of an altered motor control in PLMS, which is likely to be located subcortically and possibly related to the dopaminergic striaitopallidal system.<\/jats:p>","DOI":"10.1002\/mds.870110617","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T09:49:04Z","timestamp":1104486544000},"page":"710-714","source":"Crossref","is-referenced-by-count":27,"title":["Blink reflex excitability is abnormal in patients with periodic leg movements in sleep"],"prefix":"10.1002","volume":"11","author":[{"given":"Regula S.","family":"Briellmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai M.","family":"R\u00f6sler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian W.","family":"Hess","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,11,4]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"547","article-title":"A propos de quelques manifestations nocturnes myocloniques","volume":"115","author":"Lugaresi E","year":"1966","journal-title":"Rev Neurol"},{"key":"e_1_2_1_3_2","first-page":"469","article-title":"Periodic limb movements in sleep in community\u2010dwelling elderly","volume":"14","author":"Anconi\u2010Israel S","year":"1991","journal-title":"Sleep"},{"key":"e_1_2_1_4_2","first-page":"443","volume-title":"Update on the neurology of sleep","author":"Hening W","year":"1994"},{"doi-asserted-by":"publisher","key":"e_1_2_1_5_2","DOI":"10.1002\/ana.410080413"},{"doi-asserted-by":"publisher","key":"e_1_2_1_6_2","DOI":"10.1093\/sleep\/8.3.239"},{"doi-asserted-by":"publisher","key":"e_1_2_1_7_2","DOI":"10.1007\/BF01253608"},{"doi-asserted-by":"publisher","key":"e_1_2_1_8_2","DOI":"10.1212\/WNL.38.12.1845"},{"doi-asserted-by":"publisher","key":"e_1_2_1_9_2","DOI":"10.1093\/sleep\/16.8.713"},{"key":"e_1_2_1_10_2","first-page":"295","article-title":"Nocturnal myoclonus and restless legs syndrome","volume":"43","author":"Lugaresi E","year":"1986","journal-title":"Adv. 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