{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T06:39:49Z","timestamp":1770014389918,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,11,4]],"date-time":"2004-11-04T00:00:00Z","timestamp":1099526400000},"content-version":"vor","delay-in-days":2683,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[1997,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present the case of an adolescent boy who developed a variety of simple and complex motor and vocal tics (Tourette\u2010like syndrome), along with inattentiveness and obsessive\u2010compulsive behaviors after cardiac surgery with cardiopulmonary bypass and profound hypothermia. A single photon emission computed tomography study 2 months after surgery showed reduced uptake in the left hemisphere and 2 years later a perfusion defect in the basal ganglia. Serial magnetic resonance imaging (MRI) studies were normal. Volumetric MRI studies were obtained 4 years after surgery and compared with published values for normal individuals and children with Tourette syndrome (TS), including subsets matched for age, sex, and handedness. Measurement of basal ganglia structures showed a right\u2010dominant asymmetry of the caudate and putamen, in part similar to findings previously reported in patients with TS. Other volumetric abnormalities included a &gt;2\u2010SD reduction of cortical gray matter, a small decrease of total cerebral volume, and increase in cerebral white matter. Although a variety of neurological problems may occur after cardiopulmonary bypass, to our knowledge this case represents the first report of a chronic tic disorder following cardiac surgery with cardiopulmonary bypass and hypothermia.<\/jats:p>","DOI":"10.1002\/mds.870120417","type":"journal-article","created":{"date-parts":[[2005,5,28]],"date-time":"2005-05-28T20:28:13Z","timestamp":1117312093000},"page":"588-592","source":"Crossref","is-referenced-by-count":22,"title":["A tourette\u2010like syndrome following cardiopulmonary bypass and hypothermia: MRI volumetric measurements"],"prefix":"10.1002","volume":"12","author":[{"given":"Harvey S.","family":"Singer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablito S.","family":"DelaCruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael T.","family":"Abrams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Charles","family":"Bean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan L.","family":"Reiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,11,4]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1995.tb11983.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410340611"},{"issue":"2","key":"e_1_2_1_4_2","first-page":"118","article-title":"Factors associated with choreoathetosis after cardiopulmonary bypass in children with congenital heart disease","volume":"86","author":"Wong PC","year":"1992","journal-title":"Circulation"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03350220071035"},{"key":"e_1_2_1_6_2","first-page":"309","article-title":"Neurologic sequelae of cardiac surgery in children","volume":"141","author":"Ferry PC","year":"1987","journal-title":"Am J Dis Child"},{"issue":"1","key":"e_1_2_1_7_2","first-page":"52","article-title":"Cerebral effects of profound hypothermia and circulatory arrest","volume":"51","author":"Aoyagi M","year":"1974","journal-title":"Circulation"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199503023320901"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(90)90064-8"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0387-7604(94)90122-8"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1993.00540080076020"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.5.950"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.5.941"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.6.1176"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.47.2.477"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0925-4927(94)90015-9"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0295-159"},{"key":"e_1_2_1_18_2","first-page":"7","article-title":"Diagnosis and classification of tics and Tourette syndrome","volume":"58","author":"Jankovic J","year":"1992","journal-title":"Adv Neurol"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.4.592"},{"key":"e_1_2_1_20_2","first-page":"183","volume-title":"Handbook of Tourette syndrome and related tic and behavioral disorders","author":"Sanchez\u2010Ramos JR","year":"1993"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.15.4.284"},{"key":"e_1_2_1_22_2","first-page":"243","volume-title":"Nuclear medicine: the state of the art of nuclear medicine in Europe","author":"Hall M","year":"1991"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0925-4927(92)90022-V"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-2998(05)80106-0"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199501000-00014"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.148.9.1240"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1992.01820090023004"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/088307389601100210"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.145.9.1089"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1995.03950170067009"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/0925-4927(94)90003-5"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/119.5.1763"},{"key":"e_1_2_1_33_2","first-page":"684","article-title":"Family study and segregation analysis of Tourette's syndrome: evidence for a mixed model of inheritance","volume":"59","author":"Walkup JW","year":"1996","journal-title":"Am J Hum Genet"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.870120417","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.870120417","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:14:56Z","timestamp":1760969696000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.870120417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,7]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,7]]}},"alternative-id":["10.1002\/mds.870120417"],"URL":"https:\/\/doi.org\/10.1002\/mds.870120417","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,7]]}}}