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Although the prevalence of dysthymia was similar in both groups (classic PD, 31%; and akinetic\u2010rigid PD, 32%), patients with akinetic\u2010rigid PD had a significantly higher prevalence of major depression (38% versus 15%, respectively; p &lt; 0.01). A stepwise regression analysis demonstrated that bradykinesia was the extrapyramidal sign with the highest correlation with Hamilton depression scale scores. Our findings demonstrate a significant association between major depression and the akinetic\u2010rigid type of PD.<\/jats:p>","DOI":"10.1002\/mds.870130109","type":"journal-article","created":{"date-parts":[[2005,5,28]],"date-time":"2005-05-28T20:35:04Z","timestamp":1117312504000},"page":"29-33","source":"Crossref","is-referenced-by-count":114,"title":["Depression in classic versus akinetic\u2010rigid Parkinson's disease"],"prefix":"10.1002","volume":"13","author":[{"given":"Sergio 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