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The genus <jats:italic>Ardisia<\/jats:italic>, consisting of approximately 500 species, is the largest genus in the Myrsinaceae family. <jats:italic>Ardisia<\/jats:italic> species are widely distributed throughout tropical and subtropical regions of the world and have been used for the treatment of cancer, hypertension, irregular menstruation, gonorrhea, diarrhea and postnatal syndromes, among others. Phytochemical studies of <jats:italic>Ardisia<\/jats:italic> species have resulted in the isolation and identification of 111 compounds, including triterpenoid saponins, quinones, phenols, coumarins, cyclic depsipepetide and flavonoids. Crude extracts and isolates from <jats:italic>Ardisia<\/jats:italic> have been reported to have in vitro and in vivo efficacies, including but not limited to anticancer, antiinflammatory, antimicrobial, antioxidant, antithrombotic and antidiabetic, antitubercular compounds. This review focuses on the medical and functional uses, phytochemical profile and pharmacological efficacies of <jats:italic>Ardisia<\/jats:italic> species over the past 15 years. This review will provide information indicating that <jats:italic>Ardisia<\/jats:italic> species represent an invaluable source of potential therapeutic compounds.<\/jats:p>","DOI":"10.1002\/med.21894","type":"journal-article","created":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T06:35:30Z","timestamp":1654583730000},"page":"1888-1929","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The ethnomedicinal and functional uses, phytochemical and pharmacology of compounds from <i>Ardisia<\/i> species: An updated review"],"prefix":"10.1002","volume":"42","author":[{"given":"Bingrui","family":"Liu","sequence":"first","affiliation":[{"name":"School of Public Health, North China University of Science and Technology  Tangshan China"},{"name":"College of Chemistry and Technology Hebei Agricultural University  Huanghua China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Engineering Research Center for Medicine, College of Pharmacy Harbin University of Commerce  Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qifeng","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Chemistry and Technology Hebei Agricultural University  Huanghua China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Charles R.","family":"Ashby","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences St. John's University  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5479-3435","authenticated-orcid":false,"given":"Hang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Co\u2010innovation Center of Henan Province for New Drug R&amp;D and Preclinical Safety, and School of Pharmaceutical Sciences Zhengzhou University  Zhengzhou Henan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8289-097X","authenticated-orcid":false,"given":"Zhe\u2010Sheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences St. John's University  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,6]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Natural Products: Drug Discovery and Development","author":"Singh IP","year":"2021"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26030607"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2004.09.037"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/15376516.2011.601355"},{"key":"e_1_2_10_6_1","volume-title":"Flora of China","author":"Delectis Florae Reipublicae Popularis Sinicae Agendae Academiae Sinicae Edita","year":"2004"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0352632"},{"issue":"3","key":"e_1_2_10_8_1","first-page":"510","article-title":"Anti\u2010diabetic plants used in Thoubal district of Manipur","volume":"9","author":"Khan MH YP","year":"2010","journal-title":"Northeast India. 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