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Long\u2010term effects include organ failure, disability, and in extreme cases, even death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Through a literature search, here we summarize what is known about the molecular etiology of anorexia nervosa and propose genetic testing for this condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Anorexia nervosa often has a familial background and shows strong heritability. Various genetic studies along with genome\u2010wide association studies have identified several genetic loci involved in molecular pathways that might lead to anorexia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Anorexia nervosa is an eating disorder with a strong genetic component that contributes to its etiology. Various genetic approaches might help in the molecular diagnosis of this disease and in devising novel therapeutic options.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mgg3.1244","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T07:46:29Z","timestamp":1588664789000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5551-7520","authenticated-orcid":false,"given":"Stefano","family":"Paolacci","sequence":"first","affiliation":[{"name":"MAGI'S LAB Rovereto Trento Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysha Karim","family":"Kiani","sequence":"additional","affiliation":[{"name":"MAGI EUREGIO Bolzano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1176-3359","authenticated-orcid":false,"given":"Elena","family":"Manara","sequence":"additional","affiliation":[{"name":"MAGI EUREGIO Bolzano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Beccari","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Rachele","family":"Ceccarini","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liborio","family":"Stuppia","sequence":"additional","affiliation":[{"name":"Department of Psychological, Health and Territorial Sciences School of Medicine and Health Sciences \"G. d'Annunzio\" University Chieti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Chiurazzi","sequence":"additional","affiliation":[{"name":"Istituto di Medicina Genomica Universit\u00e0 Cattolica del Sacro Cuore Rome Italy"},{"name":"UOC Genetica Medica Fondazione Policlinico Universitario \u201cA. 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