{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:47:03Z","timestamp":1762505223108},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T00:00:00Z","timestamp":1129680000000},"content-version":"vor","delay-in-days":3944,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[1995,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We treated 18 patients (8 males and 10 females) with bone or soft tissue tumors in the extremities by vascularized fibular grafts (VFGs). The average age was 29 years. Two had malignant soft tissue tumors in the forearm (angiosarcoma and synovial sarcoma) and the other 16 had bone tumors [osteosarcoma (8), chondrosarcoma (3), angiosarcoma (1), adamantinoma (1), and giant cell tumor (3)]. Affected sites of the bone tumor cases were tibia (5), femur (5), humerus (3), radius (2), and ulna (1). According to the surgical staging system of Enneking et al. 1 patient was in stage III, 12 in IIB, 2 in IB, and 3 in IA. The surgical margin was curative in 5 patients, wide in 9, marginal in 2, and intralesional in 2. One patient died due to lung metastasis although bone union was obtained by the VFGs. Functional results of the bone reconstruction in the remaining 17 patients were evaluated according to the modified scale of Enneking et al. The VFGs resulted in substantial bone unions in all patients except 1. Bone unions in all 17 patients occurred in less than 10 months. Overall clinical results were satisfactory. Based on a 30\u2010point scale overall clinical results ranged from 10 to 30 points with an average of 21 points. Functional evaluation in the upper extremity were, generally, superior to those in the lower extremity. Postoperative complications were 5 metastases (4 in the lung and 1 in the mediastinum) in 4 patients, 1 recurrence, and 2 fractures after obtaining bone union. One patient died from metastasis. These results suggest that the VFG is effective for salvaging limb function where a massive bone defect results from wide resection of tumor in the extremities. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/micr.1920160204","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T00:08:43Z","timestamp":1173053323000},"page":"56-64","source":"Crossref","is-referenced-by-count":45,"title":["Vascularized fibular graft for bone reconstruction of the extremities after tumor resection in limb\u2010saving procedures"],"prefix":"10.1002","volume":"16","author":[{"given":"Akio","family":"Minami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Kutsumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Kaneda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,19]]},"reference":[{"key":"e_1_2_1_2_2","series-title":"Colston Paper No. 8","first-page":"265","volume-title":"Bone\u2010Certain Aspect of Neoplasia","author":"Cortes EP","year":"1973"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19841201)54:2 <2695::AID-CNCR2820541415>3.0.CO;2-O"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.2106\/00004623-198062070-00001","article-title":"Autogenous cortical bone grafts in the reconstruction of segmental skeletal defects","volume":"62","author":"Enneking WF","year":"1980","journal-title":"J Bone Joint Surg"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197212)30:6<1627::AID-CNCR2820300631>3.0.CO;2-H"},{"key":"e_1_2_1_6_2","first-page":"217","article-title":"Local en bloc resection for limb preservation","volume":"62","author":"Jaffe N","year":"1978","journal-title":"Cancer Treat Rep"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820815)50:4<613::AID-CNCR2820500402>3.0.CO;2-L"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00003086-198305000-00006","article-title":"Use of free vascularized bone grafts in the treatment of bone tumors","volume":"175","author":"Moore JR","year":"1983","journal-title":"Clin Orthop"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"602","DOI":"10.2106\/00004623-198466040-00016","article-title":"Effects of chemotherapeutic agents on bone. 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Short\u2010term methotrexate and doxorubicin (adriamycin) treatment in a rat model","volume":"66","author":"Friedlaender GE","year":"1984","journal-title":"J Bone Joint Surg"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1920070106"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1007005"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1006983"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0030-5898(20)30391-6","article-title":"The use of frozen cadaveric allografts in the management of patients with bone tumors of the extremities","volume":"18","author":"Mankin HJ","year":"1987","journal-title":"Orthop Clin North Am"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453678809149397"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1920130504"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197601)37:1<1::AID-CNCR2820370102>3.0.CO;2-3"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1920080302"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1920110405"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/00003086-198011000-00013","article-title":"A system for the surgical staging of musculoskeletal sarcoma","volume":"153","author":"Enneking WF","year":"1980","journal-title":"Clin Orthop"},{"key":"e_1_2_1_20_2","first-page":"194","article-title":"A system for the surgical staging of musculoskeletal sarcoma","volume":"17","author":"Kawaguchi T","year":"1990","journal-title":"Orthop Surg"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-197209000-00006"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199173080-00002"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.1920160204","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.1920160204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T22:20:40Z","timestamp":1698358840000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.1920160204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1995,1]]}},"alternative-id":["10.1002\/micr.1920160204"],"URL":"https:\/\/doi.org\/10.1002\/micr.1920160204","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,1]]}}}