{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T02:12:51Z","timestamp":1782526371850,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,7,11]],"date-time":"2008-07-11T00:00:00Z","timestamp":1215734400000},"content-version":"vor","delay-in-days":192,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Neurogenic bladder dysfunction following spinal cord injury is a major medical and social problem for which there is no ideal treatment strategy. In this study, spinal root anastomoses were performed in 10 paraplegic patients with traumatic lesions of the conus medullaris, in an attempt to reinnervate the paralyzed bladder. For the operation, the functional T11 ventral root (VR) above the lesion was transected and anastomosed to the S2 ventral roots unilaterally through a nerve graft. The T11 dorsal root was left intact as the trigger for micturition after axonal regeneration. All patients underwent urodynamic evaluation before surgery and at follow\u2010up. The mean follow\u2010up duration was 2 years. Of the 10 patients, 7 (70%) regained satisfactory bladder control within 18\u201324 months after VR microanastomosis. In these seven patients, the average bladder capacity decreased from 508 \u00b1 83 (mean \u00b1 SD) to 370 \u00b1 59 ml, residual urine decreased from 477 \u00b1 98 to 35 \u00b1 11 ml, and urinary infections were not observed. Patients with impaired renal function experienced a full recovery. Three patients failed to show any improvement after the operation. These results suggest that a restitutive process occurs in the bladder following reinnervation from new T11 VR connections to the bladder nerves. Spinal cord lesions that may benefit from such a nerve crossover surgery are those located at the conus, whereby a functional suprasacral nerve can be connected to the sacral roots to bypass the injury in an attempt to restore central connections to the bladder. \u00a9 2008 Wiley\u2010Liss, Inc. Microsurgery, 2008.<\/jats:p>","DOI":"10.1002\/micr.20504","type":"journal-article","created":{"date-parts":[[2008,7,11]],"date-time":"2008-07-11T16:59:59Z","timestamp":1215795599000},"page":"429-435","source":"Crossref","is-referenced-by-count":30,"title":["Reconstruction of reflex pathways to the atonic bladder after conus medullaris injury: Preliminary clinical results"],"prefix":"10.1002","volume":"28","author":[{"given":"Haodong","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Lin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guibin","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingpin","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shibo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.1994.126"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36862-3"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0094-0143(21)00075-6","article-title":"Bladder denervation procedures","volume":"6","author":"Torrens M","year":"1979","journal-title":"Urol Clin North Am"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365596809135368"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365597209133635"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101574"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199909010-00094"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000080710.32964.d0"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198001000-00007"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365597209133635"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)45141-X"},{"key":"e_1_2_1_13_2","first-page":"280","article-title":"Long\u2010term functional study on the artificial bladder reflex arc established by abdominal reflex after spinal cord injury","volume":"25","author":"Wang JW","year":"2002","journal-title":"Chin J Microsurg"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64569-7"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20014"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)65150-4"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199708000-00020"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)44356-4"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1920120403"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)45141-X"},{"key":"e_1_2_1_21_2","first-page":"73","article-title":"Reconstruction of efferent pathway to the urinary bladder in a paraplegic child","volume":"24","author":"Carlsson CA","year":"1967","journal-title":"Rev Surg"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365597209133635"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365597209133634"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(87)90168-3"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.1994.52"},{"key":"e_1_2_1_26_2","first-page":"812","article-title":"Experiment study on the artificial bladder reflex arc established in therapy of flaccid bladder after spinal cord injury","volume":"20","author":"Zhong GB","year":"2006","journal-title":"Chin J Repar Reconstr Surg"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.20504","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.20504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T20:54:00Z","timestamp":1699995240000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.20504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1002\/micr.20504"],"URL":"https:\/\/doi.org\/10.1002\/micr.20504","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}