{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:42:57Z","timestamp":1790109777470,"version":"4.0.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,3,16]],"date-time":"2010-03-16T00:00:00Z","timestamp":1268697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objectives:<\/jats:italic> To report the wide clinical experience and the research studies in the microsurgical treatment of peripheral lymphedema. <jats:italic>Methods:<\/jats:italic> More than 1800 patients with peripheral lymphedema have been treated with microsurgical techniques. Derivative lymphatic microvascular procedures recognize today its most exemplary application in multiple lymphatic\u2010venous anastomoses (LVA). In case of associated venous disease reconstructive lymphatic microsurgery techniques have been developed. Objective assessment was undertaken by water volumetry and lymphoscintigraphy. <jats:italic>Results:<\/jats:italic> Subjective improvement was noted in 87% of patients. Objectively, volume changes showed a significant improvement in 83%, with an average reduction of 67% of the excess volume. Of those patients followed\u2010up, 85% have been able to discontinue the use of conservative measures, with an average follow\u2010up of more than 10 years and average reduction in excess volume of 69%. There was a 87% reduction in the incidence of cellulitis after microsurgery. <jats:italic>Conclusions:<\/jats:italic> Microsurgical LVA have a place in the treatment of peripheral lymphedema, and should be the therapy of choice in patients who are not sufficiently responsive to nonsurgical treatment. \u00a9 2010 Wiley\u2010Liss, Inc. Microsurgery, 2010.<\/jats:p>","DOI":"10.1002\/micr.20737","type":"journal-article","created":{"date-parts":[[2010,3,16]],"date-time":"2010-03-16T19:16:59Z","timestamp":1268767019000},"page":"256-260","source":"Crossref","is-referenced-by-count":191,"title":["Microsurgery for lymphedema: Clinical research and long\u2010term results"],"prefix":"10.1002","volume":"30","author":[{"given":"Corradino","family":"Campisi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Bellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Campisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Accogli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio","family":"Bonioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Boccardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,3,16]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"62","article-title":"Unexpected histopathological findings in peripheral lymphedema","volume":"33","author":"Dellach\u00e0 A","year":"2000","journal-title":"Lymphology"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.21728"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7252-4"},{"key":"e_1_2_1_5_2","first-page":"390","article-title":"The big angiodysplastic syndromes in pediatrics with the participation of the lymphatic system","volume":"31","author":"Papendieck CM","year":"1998","journal-title":"Lymphology"},{"key":"e_1_2_1_6_2","first-page":"562","article-title":"Post\u2010surgical lymphedema: Latrogenic or pre\u2010existing disease?","volume":"31","author":"Dellach\u00e0 A","year":"1998","journal-title":"Lymphology"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.2.96"},{"key":"e_1_2_1_8_2","first-page":"989","article-title":"Frequency of lymphedema of the upper limb after treatment of breast cancer. 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A propos of 683 cases","volume":"83","author":"Ferrandez JC","year":"1996","journal-title":"Bull Cancer"},{"key":"e_1_2_1_9_2","first-page":"20","article-title":"Terapia funzionale completa del linfedema (CLyFT: complete lymphedema functional therapy): Efficace strategia terapeutica in 3 fasi","volume":"1","author":"Campisi C","year":"2008","journal-title":"Linfologia"},{"key":"e_1_2_1_10_2","first-page":"9","article-title":"Diagnostic protocol for lymphoscintigraphy in newborns","volume":"38","author":"Bellini C","year":"2005","journal-title":"Lymphology"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19981215)83:12B <2805::AID-CNCR30>3.0.CO;2-F"},{"key":"e_1_2_1_12_2","first-page":"316","article-title":"The current role of lymphoscintigraphy in the diagnostic evaluation of patients with peripheral lymphedema","volume":"31","author":"Mariani G","year":"1998","journal-title":"Lymphology"},{"key":"e_1_2_1_13_2","first-page":"343","article-title":"Lymphoscintigraphy. 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