{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T03:39:56Z","timestamp":1770435596086,"version":"3.49.0"},"reference-count":11,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2010,1,4]],"date-time":"2010-01-04T00:00:00Z","timestamp":1262563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Among possible causes of a condition of immunodeficiency, we have to consider the presence of a serious chylous dysplasia, due to the great loss of proteins through the intestinal lumen. A 20\u2010year\u2010old male, suffered from diarrhoea (2\u20134 times a day), weight loss (8 kilos in 5 years), and malnutrition (hypogammaglobulinemia, hypoalbuminemia, leukocytopenia with lymphocytopenia). Accurate diagnostic assessment allowed to diagnose a protein\u2010losing enteropathy. Conventional oil contrast lymphangiography allowed to accurately assess the case and to establish a proper therapeutic approach. The operation consisted in multiple antigravitational ligatures of dilated and incompetent chylous vessels and chylous vessel\u2010mesenteric vein microanastomoses. Parameters concerning albumin and leukocytes normalized in 1 week after operation and remained stable with time; there were no more episodes of diarrhoea and the patient recovered weight. An accurate diagnostic assessment and above all lymphangiography allow to diagnose properly difficult cases of immunodeficiency due to intestinal protido\u2010dispersion and to plan a correct therapeutic functional approach. \u00a9 2010 Wiley\u2010Liss, Inc. Microsurgery 30:401\u2013404, 2010.<\/jats:p>","DOI":"10.1002\/micr.20744","type":"journal-article","created":{"date-parts":[[2010,1,4]],"date-time":"2010-01-04T16:35:50Z","timestamp":1262622950000},"page":"401-404","source":"Crossref","is-referenced-by-count":7,"title":["Diagnostic assessment and therapeutic approach for immunodeficiency due to chylous dysplasia: A case report"],"prefix":"10.1002","volume":"30","author":[{"given":"Francesco","family":"Boccardo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Bellini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margherita","family":"Girino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrado","family":"Campisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Vidali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gino Roberto","family":"Corazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corradino","family":"Campisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,1,4]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20347"},{"key":"e_1_2_4_3_2","volume-title":"Diseases of the Lymphatics","author":"Browse N","year":"2003"},{"key":"e_1_2_4_4_2","volume-title":"The Chyliferous Vessels","author":"Servelle M","year":"1981"},{"key":"e_1_2_4_5_2","first-page":"145","article-title":"Chyloed\u00e8mes","volume":"13","author":"Casaccia M","year":"1988","journal-title":"J Mal Vasc"},{"key":"e_1_2_4_6_2","first-page":"65","volume-title":"Regulation of Angiogenesis","author":"Witte MH","year":"1996"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.21728"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2000.109502"},{"key":"e_1_2_4_9_2","volume-title":"The lymphatics. Surgery, Lymphography, and Diseases of the Chyle and Lymph Systems","author":"Kinmonth JB","year":"1982"},{"key":"e_1_2_4_10_2","volume-title":"Lymphoedema, Basic Mechanism, Clinical Problems, Indications for Therapy. Chylous Reflux","author":"Gruwez J","year":"1973"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-96-3-358"},{"key":"e_1_2_4_12_2","first-page":"10","article-title":"Chylous reflux pathologies: Diagnosis and microsurgical treatment","volume":"18","author":"Campisi C","year":"1999","journal-title":"Int Angiol"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.20744","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.20744","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.20744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T17:55:23Z","timestamp":1700589323000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.20744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,4]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.1002\/micr.20744"],"URL":"https:\/\/doi.org\/10.1002\/micr.20744","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,4]]}}}