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In ANG group, 10 mm segment from sciatic nerve was excised and reimplanted between the nerve stumps. In the SS, PRP, and PRF groups, 5 mm segment from sciatic nerve was excised and bridged with a 12 mm silicone conduit to create a 10 mm nerve gap. The conduit was filled in accordance with the different treatments. Walking track analysis was performed periodically and on the 90th post\u2010operative day histomorphometric analysis was performed. The ANG, PRF, and PRP groups presented a significant functional improvement in relation to the SS group (<jats:italic>P<\/jats:italic> = 0.001) on 90 days after surgery. Histomorphometric analysis demonstrated that the ANG group achieved a larger nerve fiber diameter in proximal stump while comparing with the SS group (<jats:italic>P<\/jats:italic> =0.037) and showed larger fiber diameter in median stump in comparison to the PRP group (<jats:italic>P<\/jats:italic> = 0.002) and PRF group (<jats:italic>P<\/jats:italic> = 0.001). Axonal diameter and myelin sheath thickness showed no statistical significant difference between the groups in the three stumps (<jats:italic>P<\/jats:italic> \u2265 0.05). This study suggests that PRP and PRF have positive effects on the functional nerve recovery; however, these groups don't achieve a significant improvement on the histomorphometric analysis. \u00a9 2013 Wiley Periodicals, Inc. 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