{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T17:27:45Z","timestamp":1750181265578},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,1,21]],"date-time":"2014-01-21T00:00:00Z","timestamp":1390262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>In women with early\u2010stage breast cancer, breast\u2010conserving therapy (BCT) provides comparable survival to mastectomy. BCT has the advantage of preserving most of the breast, its skin envelope and the nipple\u2013areola complex. However, deformity may result from the excision of significant amounts of breast tissue, as well as radiation therapy. Several studies have compared patients who underwent BCT to different patients who underwent mastectomy and reconstruction, and found superior aesthetic outcomes in the latter group. Our goal in this study was to compare the aesthetic outcomes in the same women who underwent BCT followed by mastectomy and reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2007 and 2012, 42 women with a history of BCT developed cancer recurrence and underwent mastectomy and microsurgical breast reconstruction at our institution. Photographs before and after mastectomy and reconstruction were rated by a panel of nine judges (two independent plastic surgeons, three surgical oncologists, one radiation oncologist, one medical oncologist, and two medical students), using a validated scale<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, patients received a significantly higher aesthetic score after mastectomy and reconstruction than after BCT. The greatest areas of aesthetic improvement were breast volume, contour, and projection. Patients whose lumpectomy was in the lower inner quadrant, those undergoing bilateral mastectomy and reconstruction and those completing all stages of their reconstruction had the greatest aesthetic improvement<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>When advising patients with early\u2010stage breast cancer, the superior aesthetic outcome of mastectomy and microsurgical reconstruction compared to BCT must be weighed against disadvantages such as loss of sensation, length of surgery, and donor\u2010site morbidity. \u00a9 2014 Wiley Periodicals, Inc. Microsurgery 35:21\u201328, 2015.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.22225","type":"journal-article","created":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T05:01:06Z","timestamp":1390366866000},"page":"21-28","source":"Crossref","is-referenced-by-count":6,"title":["Aesthetic outcomes in women undergoing breast\u2010conserving therapy followed by mastectomy and microsurgical reconstruction"],"prefix":"10.1002","volume":"35","author":[{"given":"Ibrahim","family":"Khansa","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery The Ohio State University Wexner Medial Center Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Iv","given":"James H.","family":"Boehmler","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery The Ohio State University Wexner Medial Center Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022152"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1996.14.5.1558"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000142442.62956.78"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000138813.64478.A7"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(03)00198-X"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-006-0163-z"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-006-0270-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020989"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e3182166b81"},{"key":"e_1_2_6_11_1","first-page":"405","article-title":"Esthetic results of breast reconstruction after amputation for cancer: 323 cases","volume":"21","author":"Garbay JR","year":"1992","journal-title":"J Gynecol Obstet Biol Reprod"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31822b669f"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e31815b6ced"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198605000-00006"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.07.029"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02967189"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1989.01410120015004"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4344"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322010000800007"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2007.01.009"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.22124"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.22081"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23214"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.22225","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.22225","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.22225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T22:25:20Z","timestamp":1696458320000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.22225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,21]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1002\/micr.22225"],"URL":"https:\/\/doi.org\/10.1002\/micr.22225","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,21]]}}}