{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T21:44:30Z","timestamp":1789854270751,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T00:00:00Z","timestamp":1507507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Innervated muscle transfer can improve functional outcomes after extensive limb\u2010sparing sarcoma resections. We report our experience using composite thigh flaps for functional reconstruction of large oncologic extremity defects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>Between 2011 and 2014, four limb\u2010sparing oncologic resections (3 lower extremities, 1 upper extremity) underwent immediate functional reconstruction with composite thigh free flaps in three males and one female. The age of the patients ranged from 36 to 73 years. There were 3 soft\u2010tissue sarcomas and one giant cell tumor, all required resection of entire muscle compartments. Flap components included fasciocutaneous tissue with sensory nerve, plicated iliotibial band (ITB), and variable amounts of motorized vastus lateralis (VL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All flaps survived without complications. All patients showed VL motor innervation by six months. Follow\u2010up ranged from 20 to 36 months. Motor strength ranged from 2 to 5 out of 5, active range of motion was 25\u201392% of normal, and Musculoskeletal Tumor Society (MSTS) Scores were between 22 and 29 out of 30.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Limb\u2010sparing techniques for upper and lower extremity sarcomas continue to evolve. Our experience has validated the composite thigh free flap as an excellent option for one\u2010stage functional reconstruction of large limb defects.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.30254","type":"journal-article","created":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T09:04:37Z","timestamp":1507539877000},"page":"466-472","source":"Crossref","is-referenced-by-count":14,"title":["Limb\u2010sparing sarcoma reconstruction with functional composite thigh flaps"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9770-6127","authenticated-orcid":false,"given":"John T.","family":"Stranix","sequence":"first","affiliation":[{"name":"Hansjorg Wyss Department of Plastic Surgery NYU Langone Medical Center New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z\u2010Hye","family":"Lee","sequence":"additional","affiliation":[{"name":"Hansjorg Wyss Department of Plastic Surgery NYU Langone Medical Center New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretl","family":"Lam","sequence":"additional","affiliation":[{"name":"Hansjorg Wyss Department of Plastic Surgery NYU Langone Medical Center New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Mirrer","sequence":"additional","affiliation":[{"name":"Hansjorg Wyss Department of Plastic Surgery NYU Langone Medical Center New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Rapp","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery NYU Langone Medical Center New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre B.","family":"Saadeh","sequence":"additional","affiliation":[{"name":"Hansjorg Wyss Department of Plastic Surgery NYU Langone Medical Center New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20974"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23810"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00003086-199301000-00035","article-title":"A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system","volume":"286","author":"Enneking W. F.","year":"1993","journal-title":"Clinical Orthopaedics and Related Research"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1006435"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199510000-00003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.SAP.0000070433.06200.2C"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181c495ed"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197602000-00001"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20607"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10419"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-015-0060-y"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2012.06.005"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2014.04.012"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/7972318"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197009000-00002"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11552-009-9223-6"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2005.12.030"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2014.06.007"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.30254","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.30254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T21:15:29Z","timestamp":1694985329000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.30254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,9]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1002\/micr.30254"],"URL":"https:\/\/doi.org\/10.1002\/micr.30254","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,9]]}}}