{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:22:09Z","timestamp":1789345329091,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,3,30]],"date-time":"2018-03-30T00:00:00Z","timestamp":1522368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Anatomical variability of anterolateral thigh flap (ALT) perforators has been reported. The aim of this study is to assess if the use of intraoperative indocyanine green angiography (iICGA) can help surgeons to choose the ALT flap best perforator to be preserved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>A retrospective study was conducted in 28 patients with open tibial fracture, following a road traffic crash, who had undergone ALT flap. Patients were classified into two groups: ICGA group (iICGA was used to select the more reliable perforator) and control group. The mean tissue loss size of the ICGA group (<jats:italic>n<\/jats:italic>\u2009=\u200913, 11 men and 2 women, mean age: 52\u2009\u00b1\u20096 years) was of 16.6 cm \u00d7 12.2 cm. The mean defect size of the control group (<jats:italic>n<\/jats:italic>\u2009=\u200915, 14 men and 1 women, mean age: 50\u2009\u00b1\u20095.52 years) was of 15.3 cm \u00d7 11.1 cm. Statistical analysis was performed to analyze and compare the results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ICGA allowed preserving only the most functional perforator, that provided the best ALT flap perfusion in 10 out of the 13 cases (77%). ICGA allowed a significant operative time reduction (160\u2009\u00b1\u200923 vs. 202\u2009\u00b1\u200948 minutes; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). One case of distal necrosis was observed in the ICGA group (mean follow\u2010up 12.3 months), while partial skin necrosis occurred in three cases of the control group (mean follow\u2010up 13.1 months); <jats:italic>P<\/jats:italic>\u2009=\u2009.35. No additional coverage was required and a successful bone healing was observed in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings suggest that iICGA is an effective method that allows to select the most reliable ALT flap perforators and to reduce operative time.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.30326","type":"journal-article","created":{"date-parts":[[2018,3,31]],"date-time":"2018-03-31T10:46:34Z","timestamp":1522493194000},"page":"738-744","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Intraoperative use of indocyanine green angiography for selecting the more reliable perforator of the anterolateral thigh flap: A comparison study"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3543-9024","authenticated-orcid":false,"given":"Simone","family":"La Padula","sequence":"first","affiliation":[{"name":"Department of Plastic, Reconstructive and Maxillofacial Surgery Henri Mondor Hospital UPEC, Cr\u00e9teil, 94010 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Hersant","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive and Maxillofacial Surgery Henri Mondor Hospital UPEC, Cr\u00e9teil, 94010 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Paul","family":"Meningaud","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive and Maxillofacial Surgery Henri Mondor Hospital UPEC, Cr\u00e9teil, 94010 France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181858bd2"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181ef8cb7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2011.06.001"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2007.12.074"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2005.02.018"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181c495ed"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjps.2002.3969"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.10052"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(94)31303-0"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181d51655"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30004"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199810000-00026"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200009010-00009"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0007-1226(89)90142-2"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199309000-00005"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000001103"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1234023"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181adcf7d"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31824a2b02"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31819e67c1"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anplas.2010.08.003"},{"key":"e_1_2_6_23_1","first-page":"e30","article-title":"Near\u2010infrared laser\u2010assisted indocyanine green imaging for optimizing the design of the anterolateral thigh flap","volume":"12","author":"Sacks J. 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