{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:13:33Z","timestamp":1792005213268,"version":"4.4.0"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T00:00:00Z","timestamp":1530662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"No grants were involved in the production of this manuscript"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>Thoracic duct injury can be a devastating injury with disruption of lymphatic flow leading to potentially chylothorax and\/or severe lymphedema. Standard treatment modalities include thoracic duct ligation or embolization for chylothorax, but treatment options to date are few for resultant lymphedema. In this case report, we describe lymphaticovenous bypass of the thoracic duct to the jugular venous system in a 21\u2010year\u2010old male with secondary lymphedema after iatrogenic thoracic duct injury. The patient experienced improvement of lymphedema symptoms including decreased weight and limb girth as well as normalization of serum markers indicating improved lymphatic delivery to the venous system. Lymphangiogram at 3 months post op demonstrated patency of the lymphaticovenous anastomoses. At 6\u2010month follow\u2010up, the patient had returned to his preoperative level of activity and showed continued improvement of his lymphedema symptoms. Lymphovenous bypass of the thoracic duct may be an effective technique to treat secondary lymphedema from thoracic duct obstruction, though further studies are required to determine long\u2010term efficacy.<\/jats:p>","DOI":"10.1002\/micr.30339","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T05:15:09Z","timestamp":1530767709000},"page":"255-258","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Correction of complete thoracic duct obstruction with lymphovenous bypass: A case report"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4534-1258","authenticated-orcid":false,"given":"Travis J.","family":"Miller","sequence":"first","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Stanford University Palo Alto California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarom N.","family":"Gilstrap","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Stanford University Palo Alto California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhide","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Stanford University Palo Alto California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley","family":"Rockson","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Stanford University Palo Alto California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dung H.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Stanford University Palo Alto California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1273941"},{"key":"e_1_2_4_3_1","doi-asserted-by":"crossref","first-page":"742.6","DOI":"10.1096\/fasebj.27.1_supplement.742.6","article-title":"Obstruction of the thoracic duct(s) causes chronic lymphedema of the upper limb in patients presenting with symptoms of thoracic outlet syndrome: MRI\/MRA\/MRV","volume":"27","author":"Collins J. D.","year":"2013","journal-title":"FASEB Journal"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-194807000-00007"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e318212f19c"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2012.04.058"},{"key":"e_1_2_4_7_1","volume-title":"Clinical anatomy and pathology of the thoracic duct: An investigation of 122 cases","author":"Jacobsson S.\u2010I.","year":"1972"},{"key":"e_1_2_4_8_1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/micr.30200","article-title":"Serial two\u2010year follow\u2010up after lymphaticovenular anastomosis for the treatment of lymphedema","volume":"37","author":"Lee K.\u2010T.","journal-title":"Microsurgery"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.53.2822"},{"key":"e_1_2_4_10_1","first-page":"819","article-title":"Treatment options in patients with chylothorax","volume":"110","author":"Schild H. H.","year":"2013","journal-title":"Deutsches \u00c4rzteblatt International"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2006.10.006"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.30339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.30339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/micr.30339","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.30339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T06:30:58Z","timestamp":1694413858000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.30339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,4]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1002\/micr.30339"],"URL":"https:\/\/doi.org\/10.1002\/micr.30339","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,4]]},"assertion":[{"value":"2017-11-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}