{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:39:01Z","timestamp":1783489141308,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T00:00:00Z","timestamp":1548288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Limb salvage in patients with peripheral vascular disease (PVD) and soft tissue defects often requires both a restoration of blood flow to the lower extremity and soft tissue coverage. Outcomes of free tissue transfer may be affected by vein grafts, which can be used for the placement of an autologous venous bypass or an arteriovenous (AV) loop leading to different hemodynamic situations. The purpose of this study was to investigate whether free flap anastomosis to a bypass or an AV loop can be performed with comparable results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a matched\u2010pair analysis of 22 patients with PVD undergoing free flap reconstructions of the lower extremity with end\u2010to\u2010side anastomosis to an autologous venous bypass (<jats:italic>n<\/jats:italic> =\u200911, 1 female and 10 male patients) or an AV loop (<jats:italic>n<\/jats:italic> =\u200911, 2 female and 9 male patients). Defects caused by trauma, infection, ulcer, or fasciotomy were reconstructed in each group with 5 muscle\u2010based flaps, 3 parascapular flaps, 2 anterolateral thigh (ALT) flaps, and 1 conjoined latissimus dorsi and parascapular flap. Postoperative complications including thromboses, flap failures, wound complications, and hematomas were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Postoperative complication rates including 1 venous pedicle thrombosis (9%vs. 0%, <jats:italic>P<\/jats:italic> = 1.0), minor (18% vs. 9%, <jats:italic>P<\/jats:italic> = 1.0) and major wound complications (45% vs. 27%, <jats:italic>P<\/jats:italic> =\u2009.69) as well as hematomas (27% vs. 36%, <jats:italic>P<\/jats:italic> = 1.0) did not show relevant differences between the groups. Flap failures were absent in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with PVD, autologous venous bypass grafts may be used for end\u2010to\u2010side anastomoses of free flaps, with postoperative outcomes being comparable to AV loop reconstructions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.30428","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T23:12:10Z","timestamp":1548371530000},"page":"12-18","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Venous bypass grafts versus arteriovenous loops as recipient vessels for microvascular anastomosis in lower extremity reconstructions: A matched\u2010pair analysis"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4775-0151","authenticated-orcid":false,"given":"Dominic","family":"Henn","sequence":"first","affiliation":[{"name":"Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen University of Heidelberg, Ludwig\u2010Guttmann\u2010Str. 13  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8852-5132","authenticated-orcid":false,"given":"Amir K.","family":"Bigdeli","sequence":"additional","affiliation":[{"name":"Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen University of Heidelberg, Ludwig\u2010Guttmann\u2010Str. 13  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Horsch","sequence":"additional","affiliation":[{"name":"Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen University of Heidelberg, Ludwig\u2010Guttmann\u2010Str. 13  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christel","family":"Wei\u00df","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics University Medicine Mannheim, University of Heidelberg, Theodor\u2010Kutzer\u2010Ufer 1  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clemens","family":"K\u00fchner","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Ludwigshafen Hospital, Bremser Str. 79  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6112-8671","authenticated-orcid":false,"given":"Christoph","family":"Hirche","sequence":"additional","affiliation":[{"name":"Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen University of Heidelberg, Ludwig\u2010Guttmann\u2010Str. 13  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker J.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen University of Heidelberg, Ludwig\u2010Guttmann\u2010Str. 13  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Kneser","sequence":"additional","affiliation":[{"name":"Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen University of Heidelberg, Ludwig\u2010Guttmann\u2010Str. 13  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,24]]},"reference":[{"issue":"4","key":"e_1_2_7_2_1","first-page":"248","article-title":"Reconstruction of the vascular compromised lower extremity \u2010 report of the consensus workshop at the 35. Meeting of the DAM (Deutschsprachige Gemeinschaft f\u00fcr Mikrochirurgie der peripheren Nerven und Gef\u00e4\u00dfe) 2013 in Deidesheim","volume":"46","author":"Daigeler A.","year":"2014","journal-title":"Handchirurgie, Mikrochirurgie, Plastische Chirurgie"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20391"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2013.03.024"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02592666"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198609000-00001"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000005386"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.04.004"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-198908000-00005"},{"key":"e_1_2_7_10_1","first-page":"479","article-title":"Single\u2010stage versus two\u2010stage arteriovenous loop microsurgical reconstruction: A meta\u2010analysis of the literature","volume":"14","author":"Knackstedt R.","year":"2017","journal-title":"Microsurgery"},{"issue":"5","key":"e_1_2_7_11_1","first-page":"536","article-title":"Extended skin and soft tissue defects after vascular wounds: Plastic surgical concepts","volume":"138","author":"Kneser U.","year":"2013","journal-title":"Zentralblatt f\u00fcr Chirurgie"},{"issue":"1","key":"e_1_2_7_12_1","first-page":"1062","article-title":"Does the use of arteriovenous loops increase complications rates in posttraumatic microsurgical lower extremity reconstruction? A matched\u2010pair analysis","volume":"95","author":"Momeni A.","year":"2017","journal-title":"Microsurgery"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2015.02.008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.05.019"},{"key":"e_1_2_7_15_1","first-page":"15","article-title":"Head loss as an explanation of the steal phenomenon in microvascular surgery","volume":"45","author":"Ross P. E.","year":"2015","journal-title":"Eplasty. Open Science Co"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199503000-00020"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000247985.45541.e8"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmicr.30428","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.30428","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/micr.30428","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.30428","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T08:10:38Z","timestamp":1694160638000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.30428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,24]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1002\/micr.30428"],"URL":"https:\/\/doi.org\/10.1002\/micr.30428","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,24]]},"assertion":[{"value":"2018-07-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}