{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:50:16Z","timestamp":1761897016755,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Radiation\u2010induced pharyngoesophageal stenosis is a frequent and unwanted consequence of nonsurgical treatment of hypopharyngeal carcinomas. Current treatment mainly includes endoscopic dilatations, but a poor response to this modality and\/or a severe stenosis may lead to a radical resection (pharyngolaryngectomy) and reconstruction with tubed flaps, which allow oral feeding but fail to preserve speech. In this report, we present a case of radiation\u2010induced hypopharyngeal stenosis treated with a pharyngoesophageal bypass using an anterolateral thigh (ALT) flap with the intention of preserving the larynx. We describe the case of a 59\u2010year\u2010old male with severe pharyngoesophageal stenosis after chemoradiotherapy due to a squamous cell carcinoma, where conventional dilatation treatment failed to restore pharyngoesophageal passage of solids or liquids. Since the patient rejected a pharyngolaryngectomy due the loss of speech entailed, a pharyngoesophageal bypass was performed using an ALT flap. The flap measured 13\u2009\u00d7\u200920\u2009cm, which ensured a 4\u2010cm\u2010diameter tube and enough length to communicate the lateral pharyngeal wall with the cervical esophagus. Endoscopy did not reveal flap failure, and during the immediate postoperative period, the patient had a small cervical leak detected only by imaging that did not affect the skin and resolved with antibiotic treatment. The patient also required a tracheostomy on day 4 and initially had no passage of saliva through the bypass; we attributed this to edema that resolved spontaneously after 1 month with complete liquid and solid passage and laryngeal competence that led to tracheal decannulation. Good functional results were achieved both for speech and swallowing at 5\u2010year follow\u2010up. We believe that this procedure may be considered before performing a pharyngolaryngectomy for the treatment of a persistent benign stenosis in patients with a functional larynx.<\/jats:p>","DOI":"10.1002\/micr.30474","type":"journal-article","created":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T12:17:32Z","timestamp":1559650652000},"page":"543-547","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Treatment for postchemoradiotherapy hypopharyngeal stenosis: Pharyngoesophageal bypass using an anterolateral thigh flap\u2014A case report"],"prefix":"10.1002","volume":"39","author":[{"given":"Juan J.","family":"Larra\u00f1aga","sequence":"first","affiliation":[{"name":"Section of Reconstructive Surgery, Department of General Surgery Hospital Italiano de Buenos Aires  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0096-418X","authenticated-orcid":false,"given":"Luis A.","family":"Boccalatte","sequence":"additional","affiliation":[{"name":"Section of Head and Neck Surgery, Department of General Surgery Hospital Italiano de Buenos Aires  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro I.","family":"Picco","sequence":"additional","affiliation":[{"name":"Section of Head and Neck Surgery, Department of General Surgery Hospital Italiano de Buenos Aires  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetrio","family":"Cavadas","sequence":"additional","affiliation":[{"name":"Section of Esophageal and Gastric Surgery, Department of General Surgery Hospital Italiano de Buenos Aires  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo F.","family":"Figari","sequence":"additional","affiliation":[{"name":"Section of Head and Neck Surgery, Department of General Surgery Hospital Italiano de Buenos Aires  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/dow030"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(04)02789-0"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2001.117517"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000191459.40059.fd"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30135"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20427"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10365"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26618"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.06.081"},{"issue":"2","key":"e_1_2_4_11_1","first-page":"219","article-title":"Prevalence of pharyngeal and esophageal stenosis following radiation for head and neck cancer","volume":"37","author":"Nguyen N. 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